Differentiating sclerosing cholangitis caused by autoimmune pancreatitis and primary sclerosing cholangitis according to endoscopic duodenal papillary features

十二指肠大乳头 医学 原发性硬化性胆管炎 自身免疫性胰腺炎 胃肠病学 十二指肠 内科学 胰腺炎 内镜逆行胰胆管造影术 病理 疾病
作者
Kensuke Kubota,Shingo Kato,Tomoyuki Akiyama,Masato Yoneda,Koji Fujita,Masami Ogawa,Masahiko Inamori,Noritoshi Kobayashi,Satoru Saito,Yukio Kakuta,Hisashi Ohshiro,Atsushi Nakajima
出处
期刊:Gastrointestinal Endoscopy [Elsevier]
卷期号:68 (6): 1204-1208 被引量:55
标识
DOI:10.1016/j.gie.2008.08.013
摘要

Differentiating primary sclerosing cholangitis (PSC) and sclerosing cholangitis caused by autoimmune pancreatitis (SC-AIP) is often challenging. Recently, endoscopic findings of the duodenal papilla in cases with AIP or PSC were reported by Unno and Parlak, although the endoscopic differentiation of these 2 conditions has not yet been fully clarified.Our purpose was to clarify the endoscopic findings of the duodenal papilla in patients with SC-AIP and those with PSC and to determine criteria for the differentiation of these conditions.Case series.Retrospective.Twenty-seven patients with SC-AIP and 12 patients with PSC who had undergone ERCP were identified from our database. We reviewed these records to determine whether the duodenal papillary findings (swollen papilla/normal papilla/small papilla) might be potentially useful for differentiating SC-AIP and PSC. Immunohistopathological findings for the duodenal papilla were also examined by using immunoglobulin G4 (IgG4) among the infiltrating plasma cells.ERCP, biopsy specimen taken from duodenal papilla.The presence of a swollen duodenal papilla with IgG4-positive plasma cells was useful for discriminating SC-AIP from with PSC.A swollen duodenal papilla was observed in 63% (17/27) of the patients with SC-AIP, whereas there was no swelling of the duodenal papilla of the patients with PSC. A small papilla was recognized in 50% (6/12) of the patients with PSC. IgG4-positive plasma cells in the duodenal papilla were significantly detected in the patients with SC-AIP but not in the patients with PSC.Single-center study.Characteristic duodenal endoscopic papillary features in patients with SC-AIP, such as a swollen duodenal papilla and positive immunostaining for IgG4, might be helpful for discriminating this condition from PSC.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
星辰大海应助平淡的半青采纳,获得10
2秒前
顾矜应助海豚音521033采纳,获得10
2秒前
3秒前
香蕉觅云应助崔噔噔采纳,获得10
4秒前
虾米发布了新的文献求助10
4秒前
万能图书馆应助禾泽采纳,获得10
4秒前
Phosphene应助北极星采纳,获得10
5秒前
Phosphene应助北极星采纳,获得10
5秒前
Phosphene应助北极星采纳,获得10
5秒前
zpf应助北极星采纳,获得10
5秒前
6秒前
6秒前
6秒前
希望天下0贩的0应助1111采纳,获得10
7秒前
8秒前
8秒前
9秒前
ll发布了新的文献求助10
9秒前
wuming完成签到,获得积分10
9秒前
10秒前
11秒前
科研人才发布了新的文献求助10
12秒前
善学以致用应助limin采纳,获得50
13秒前
李姐驳回了大个应助
13秒前
斯文败类应助安平采纳,获得10
13秒前
橘子完成签到,获得积分10
13秒前
风趣亦凝完成签到 ,获得积分10
14秒前
14秒前
15秒前
JZJ发布了新的文献求助10
16秒前
外向半青完成签到,获得积分10
16秒前
左欣完成签到,获得积分10
16秒前
1111111111111发布了新的文献求助10
17秒前
18秒前
18秒前
21秒前
21秒前
22秒前
22秒前
高分求助中
Sustainability in ’Tides Chemistry 2000
Sustainability in ’Tides Chemistry 1500
Studien zur Ideengeschichte der Gesetzgebung 1000
The ACS Guide to Scholarly Communication 1000
TM 5-855-1(Fundamentals of protective design for conventional weapons) 1000
Handbook of the Mammals of the World – Volume 3: Primates 805
Ethnicities: Media, Health, and Coping 800
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3071903
求助须知:如何正确求助?哪些是违规求助? 2725788
关于积分的说明 7491264
捐赠科研通 2373147
什么是DOI,文献DOI怎么找? 1258476
科研通“疑难数据库(出版商)”最低求助积分说明 610277
版权声明 596944