抗菌活性
广谱
毒性
抗菌剂
纳米材料
最小抑制浓度
细菌
碳纤维
兴奋剂
材料科学
抗生素
纳米技术
化学
生物
微生物学
组合化学
有机化学
复合数
复合材料
遗传学
光电子学
作者
Yurong Ma,Mengling Zhang,Huibo Wang,Bo Wang,Hui Huang,Yang Liu,Zhenhui Kang
标识
DOI:10.1016/j.mtcomm.2020.101222
摘要
Bacterial infection is one of the most serious health hazards for people all over the world. Simultaneously, with the wide application of antibiotics, drug-resistance has become a crucial issue. Numerous nanomaterials have been studied to fight bacteria. Yet few studies point out the relationship between carbon dots (CDs) from leaves and bacteria. In this work, three kinds of N-doped CDs by one-step hydrothermal method were synthesized from osmanthus leaves, tea leaves and milk vetch, respectively, and presented different broad-spectrum antibacterial activities via stemming from the damage of the cytomembrane. Among them, at maximum inhibitory concentration of 1000 μg/mL, CDs from osmanthus leaves (OCDs) show the best antibacterial activity and only 13.09% of the E. coli and 3.37% S. aureus were alive. It is worth noting that so high concentration of OCDs owns low toxicity to cells. In contrast, CDs from milk vetch (MCDs) exhibit the worst antibacterial activity and even 70% of both species survived at the same concentration. This difference of antibacterial activity among the three CDs should put down to their diverse natural-occurring substance. This work provides a new perspective on the selectivity of low-toxicity and high-concentration carbon-based nanomaterials for broad-spectrum antibacterial materials.
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