THE SIGNIFICANCE OF SERUM COMPLEMENT LEVELS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE AND SUBACUTE GLOMERULONEPHRITIS AND LUPUS ERYTHEMATOSUS DISSEMINATUS

Article1 October 1960THE SIGNIFICANCE OF SERUM COMPLEMENT LEVELS FOR THE DIAGNOSIS AND PROGNOSIS OF ACUTE AND SUBACUTE GLOMERULONEPHRITIS AND LUPUS ERYTHEMATOSUS DISSEMINATUSKURT LANGE, M.D., F.A.C.P., EDWARD WASSERMAN, M.D., LAWRENCE B. SLOBODY, M.D.KURT LANGE, M.D., F.A.C.P., EDWARD WASSERMAN, M.D., LAWRENCE B. SLOBODY, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-53-4-636 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptSince the original publication by Veil and Buchholz1 in 1932, in which they reported a lowering of serum complement in a few cases of acute glomerulonephritis, a number of investigators have studied this phenomenon, mostly in small numbers of cases and with short-term observations only.2, 3, 4For the last 10 years5, 6we have examined serum complement levels in 3,051 patients with varied kidney diseases, in addition to examinations in a great number of normal persons, and in patients with other disease conditions. Since we felt that the determination of serum complement levels (C') is an important and often...Bibliography1. VeilBuchholz WHB: Der Komplementschwund im Blute, Klin. Wchnschr. 11: 2019, 1932. CrossrefGoogle Scholar2. 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Y.Requests for reprints should be addressed to Kurt Lange, M.D., New York Medical College, 1 East 105th Street, New York 29, N. Y. 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