Evaluation of Serum Lipoprotein and Cholesterol Measurements as Predictors of Clinical Complications of Atherosclerosis

HomeCirculationVol. 14, No. 4Evaluation of Serum Lipoprotein and Cholesterol Measurements as Predictors of Clinical Complications of Atherosclerosis Free AccessResearch ArticlePDF/EPUBAboutView PDFSections ToolsAdd to favoritesDownload citationsTrack citationsPermissions ShareShare onFacebookTwitterLinked InMendeleyReddit Jump toFree AccessResearch ArticlePDF/EPUBEvaluation of Serum Lipoprotein and Cholesterol Measurements as Predictors of Clinical Complications of Atherosclerosis Report of a Cooperative Study of Lipoproteins and Atherosclerosis JOHN W. GOFMAN, MARTIN HANIG, HARDIN B. JONES, MAX A. LAUFFER, ELEANOR Y. LAWRY, LENA A. LEWIS, GEORGE V. MANN, FELIX E. MOORE, FREDERICK OLMSTED, J. FRANKLIN YEAGER, E. COWLES ANDRUS, J. H. BARACH, J. W. BEAMS, JOHN W. FERTIG, JOHN W. GOFMAN, MAX A. LAUFFER, IRVINE H. PAGE, JAMES A. SHANNON, FREDRICK J. STARE and PAUL D. WHITE JOHN W. GOFMANJOHN W. GOFMAN Search for more papers by this author , MARTIN HANIGMARTIN HANIG Search for more papers by this author , HARDIN B. JONESHARDIN B. JONES Search for more papers by this author , MAX A. LAUFFERMAX A. LAUFFER Search for more papers by this author , ELEANOR Y. LAWRYELEANOR Y. LAWRY Search for more papers by this author , LENA A. LEWISLENA A. LEWIS Search for more papers by this author , GEORGE V. MANNGEORGE V. MANN Search for more papers by this author , FELIX E. MOOREFELIX E. MOORE Search for more papers by this author , FREDERICK OLMSTEDFREDERICK OLMSTED Search for more papers by this author , J. FRANKLIN YEAGERJ. FRANKLIN YEAGER Search for more papers by this author , E. COWLES ANDRUSE. COWLES ANDRUS Search for more papers by this author , J. H. BARACHJ. H. BARACH Search for more papers by this author , J. W. BEAMSJ. W. BEAMS Search for more papers by this author , JOHN W. FERTIGJOHN W. FERTIG Search for more papers by this author , JOHN W. GOFMANJOHN W. GOFMAN Search for more papers by this author , MAX A. LAUFFERMAX A. LAUFFER Search for more papers by this author , IRVINE H. PAGEIRVINE H. PAGE Search for more papers by this author , JAMES A. SHANNONJAMES A. SHANNON Search for more papers by this author , FREDRICK J. STAREFREDRICK J. STARE Search for more papers by this author and PAUL D. WHITEPAUL D. WHITE Search for more papers by this author Originally published1 Oct 1956https://doi.org/10.1161/01.CIR.14.4.689Circulation. 1956;14:689–741 Previous Back to top Next FiguresReferencesRelatedDetailsCited By Moore B and Cook G (2022) Medicinal chemistry and pharmacology of statins Cholesterol, 10.1016/B978-0-323-85857-1.00012-2, (903-926), . Blackburn H (2021) John ‘Jack’ Gofman. Researcher and Social Activist., The American Journal of Cardiology, 10.1016/j.amjcard.2021.05.051, 154, (111-117), Online publication date: 1-Sep-2021. Lordan R, Tsoupras A and Zabetakis I (2019) The Lipid Hypothesis and the Seven Countries Study The Impact of Nutrition and Statins on Cardiovascular Diseases, 10.1016/B978-0-12-813792-5.00004-5, (119-143), . Varbo A, Benn M and Nordestgaard B (2014) Remnant cholesterol as a cause of ischemic heart disease: Evidence, definition, measurement, atherogenicity, high risk patients, and present and future treatment, Pharmacology & Therapeutics, 10.1016/j.pharmthera.2013.11.008, 141:3, (358-367), Online publication date: 1-Mar-2014. Varbo A and Nordestgaard B (2014) Remnant cholesterol and ischemic heart disease, Current Opinion in Lipidology, 10.1097/MOL.0000000000000093, 25:4, (266-273), Online publication date: 1-Aug-2014. Varbo A, Benn M, Tybjærg-Hansen A, Jørgensen A, Frikke-Schmidt R and Nordestgaard B (2013) Response, Journal of the American College of Cardiology, 10.1016/j.jacc.2013.08.1615, 62:20, (1908-1909), Online publication date: 1-Nov-2013. Williams P (2012) Low High‐Density Lipoprotein 3 Reduces the Odds of Men Surviving to Age 85 During 53‐Year Follow‐Up, Journal of the American Geriatrics Society, 10.1111/j.1532-5415.2011.03851.x, 60:3, (430-436), Online publication date: 1-Mar-2012. Williams P (2012) Fifty-three year follow-up of coronary heart disease versus HDL2 and other lipoproteins in Gofman's Livermore Cohort, Journal of Lipid Research, 10.1194/jlr.M019356, 53:2, (266-272), Online publication date: 1-Feb-2012. (2012) CardioPulse Articles, European Heart Journal, 10.1093/eurheartj/ehs364, 33:23, (2883-2891), Online publication date: 1-Dec-2012., Online publication date: 1-Dec-2012. Wilson P (2008) Progressing From Risk Factors to Omics, Circulation: Cardiovascular Genetics, 1:2, (141-146), Online publication date: 1-Dec-2008. McNamara J, Warnick G and Cooper G (2006) A brief history of lipid and lipoprotein measurements and their contribution to clinical chemistry, Clinica Chimica Acta, 10.1016/j.cca.2006.02.041, 369:2, (158-167), Online publication date: 1-Jul-2006. Miwa K, Nakagawa K, Suzuki K and Inoue H (2001) Detection of the “midband” lipoprotein in patients with coronary artery spasm, Clinical Cardiology, 10.1002/clc.4960240309, 24:3, (219-224), Online publication date: 1-Mar-2001. Lauffer M (2000) Chapter 4 Half a century with TMV and biophysics Selected Topics in the History of Biochemistry Personal Recollections. VI, 10.1016/S0069-8032(00)41008-9, (169-273), . Soloff L (1998) Intermediate Lipoproteins, Atherosclerosis, and Gofman, Circulation, 97:7, (708-708), Online publication date: 24-Feb-1998. Dahlén , Weinehall , Weinehall , Stenlund , Jansson , Hallmans , Huhtasaari and Wall (2002) Lipoprotein(a) and cholesterol levels act synergistically and apolipoprotein A‐I is protective for the incidence of primary acute myocardial infarction in middle‐aged males. An incident case–control study from Sweden, Journal of Internal Medicine, 10.1046/j.1365-2796.1998.00422.x, 244:5, (425-430), Online publication date: 1-Nov-1998. Epstein F (1996) Cardiovascular Disease Epidemiology, Circulation, 10.1161/01.CIR.93.9.1755, 93:9, (1755-1764), Online publication date: 1-May-1996. Shively C, Knox S, Sherwin B, Walsh B and Wilson P (1993) Sex steroids, psychosocial factors, and lipid metabolism, Metabolism, 10.1016/0026-0495(93)90256-N, 42:9, (16-24), Online publication date: 1-Sep-1993. Richmond W (2016) Analytical Reviews in Clinical Biochemistry: The Quantitative Analysis of Cholesterol, Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 10.1177/000456329202900601, 29:6, (577-597), Online publication date: 1-Nov-1992. O'Holohan D (1992) Nutritional advice for cardiac patients, Nutrition Research, 10.1016/S0271-5317(05)80452-X, 12, (S69-S83), Online publication date: 1-Jan-1992. Castelli W (1992) Epidemiology of triglycerides: A view from Framingham, The American Journal of Cardiology, 10.1016/0002-9149(92)91083-G, 70:19, (H3-H9), Online publication date: 1-Dec-1992. Castelli W (1992) Whither Triglycerides in the Cholesterol Campaign Multiple Risk Factors in Cardiovascular Disease, 10.1007/978-94-011-2700-4_29, (225-228), . Kreger B, Anderson K, Schatzkin A and Splansky G (1992) Serum cholesterol level, body mass index, and the risk of colon cancer. The framingham study, Cancer, 10.1002/1097-0142(19920901)70:5<1038::AID-CNCR2820700505>3.0.CO;2-M, 70:5, (1038-1043), Online publication date: 1-Sep-1992. Hauss W (1990) Pathogenese der Arteriosklerose, insbesondere der Koronarsklerose Die Arteriosklerose, 10.1007/978-3-642-72441-1_5, (99-196), . Frost P, Verter J and Miller D (1987) Serum lipids and lipoproteins after myocardial infarction: Associations with cardiovascular mortality and experience in the Aspirin Myocardial Infarction Study, American Heart Journal, 10.1016/0002-8703(87)90648-X, 113:6, (1356-1364), Online publication date: 1-Jun-1987. Ellison R and Cohn P (1985) Prevention of Coronary Atherosclerosis Diagnosis and Therapy of Coronary Artery Disease, 10.1007/978-1-4613-2569-7_11, (283-303), . Gustafsson I, Vessby B, Karlström B, Boberg J, Boberg M and Lithell H (1985) Effects on the serum lipoprotein concentrations by lipid-lowering diets with different fatty acid compositions., Journal of the American College of Nutrition, 10.1080/07315724.1985.10720080, 4:2, (241-248), Online publication date: 1-Jan-1985. Ritchey M, Sago A and Novicki D (1985) Effect of Vasectomy on High Density Lipoproteins, Journal of Urology, 10.1016/S0022-5347(17)48775-1, 133:1, (42-44), Online publication date: 1-Jan-1985. Abbott R, Garrison R, Wilson P, Epstein F, Castelli W, Feinleib M and LaRue C (1983) Joint distribution of lipoprotein cholesterol classes. The Framingham study., Arteriosclerosis: An Official Journal of the American Heart Association, Inc., 3:3, (260-272), Online publication date: 1-May-1983. Cattran D (2020) The Significance of Lipid Abnormalities in Patients Receiving Dialysis Therapy, Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis, 10.1177/089686088300303S10, 3:3_suppl, (29-32), Online publication date: 1-Aug-1983. Vega G, Illingworth D, Grundy S, Lindgren F and Connor W (1983) Normocholesterolemic tendon xanthomatosis with overproduction of apolipoprotein B, Metabolism, 10.1016/0026-0495(83)90215-9, 32:2, (118-125), Online publication date: 1-Feb-1983. Lees R and Lees A (1982) High-Density Lipoproteins and the Risk of Atherosclerosis, New England Journal of Medicine, 10.1056/NEJM198206243062509, 306:25, (1546-1548), Online publication date: 24-Jun-1982. Tatami R, Mabuchi H, Ueda K, Ueda R, Haba T, Kametani T, Ito S, Koizumi J, Ohta M, Miyamoto S, Nakayama A, Kanaya H, Oiwake H, Genda A and Takeda R (1981) Intermediate-density lipoprotein and cholesterol-rich very low density lipoprotein in angiographically determined coronary artery disease., Circulation, 64:6, (1174-1184), Online publication date: 1-Dec-1981. Zülch K (1981) Cerebrovascular Pathology and Pathogenesis as a Basis of Neuroradiological Diagnosis Röntgendiagnostik des Zentralnervensystems / Roentgen Diagnosis of the Central Nervous System, 10.1007/978-3-642-95333-0_1, (1-192), . Watanabe A, Yoshimura A, Wakasugi T, Tatami R, Ueda K, Ueda R, Haba T, Kametani T, Koizumi J, Ito S, Ohta M, Miyamoto S, Mabuchi H and Takeda R (1981) Serum lipids, lipoprotein lipids and coronary heart disease in patients with xanthelasma palpebrarum, Atherosclerosis, 10.1016/0021-9150(81)90044-7, 38:3-4, (283-290), Online publication date: 1-Feb-1981. Myant N (1981) Cholesterol and Atherosclerosis The Biology of Cholesterol and Related Steroids, 10.1016/B978-0-433-22880-6.50020-5, (603-668), . Heiss G, Tamir I, Davis C, Tyroler H, Rifkand B, Schonfeld G, Jacobs D and Frantz I (1980) Lipoprotein-cholesterol distributions in selected North American populations: the lipid research clinics program prevalence study., Circulation, 61:2, (302-315), Online publication date: 1-Feb-1980. Brussaard J, Dallinga-Thie G, Groot P and Katan M (1980) Effects of amount and type of dietary fat on serum lipids, lipoproteins and apolipoproteins in man, Atherosclerosis, 10.1016/0021-9150(80)90244-0, 36:4, (515-527), Online publication date: 1-Aug-1980. Gordon T (1980) Epidemiology and High Density Lipoproteins Atherosclerosis V, 10.1007/978-1-4612-6071-4_97, (495-499), . Schettler G and Comberg H (1980) Hypertonie und Arteriosklerose Arterielle Hypertonie, 10.1007/978-3-642-96451-0_4, (41-54), . Keys A (1980) ALPHA LIPOPROTEIN (HDL) CHOLESTEROL IN THE SERUM AND THE RISK OF CORONARY HEART DISEASE AND DEATH, The Lancet, 10.1016/S0140-6736(80)90280-9, 316:8195, (603-606), Online publication date: 1-Sep-1980. Seidel D and Wieland H (1980) Significance and Need of Screening for Hyperlipidemia in Childhood Neonatal Screening for Inborn Errors of Metabolism, 10.1007/978-3-642-67488-4_11, (123-131), . Hollander W, Paddock J and Colombo M (1979) Lipoproteins in human atherosclerotic vessels, Experimental and Molecular Pathology, 10.1016/0014-4800(79)90051-0, 30:2, (144-171), Online publication date: 1-Apr-1979. (1978) Natural history of myocardial infarction in the coronary drug project: Long-term prognostic importance of serum lipid levels, The American Journal of Cardiology, 10.1016/0002-9149(78)90946-3, 42:3, (489-498), Online publication date: 1-Sep-1978. Mann G (1977) Diet-Heart: End of an Era, New England Journal of Medicine, 10.1056/NEJM197709222971206, 297:12, (644-650), Online publication date: 22-Sep-1977. Nilsson G, Nordlander S and Levin K (2009) Studies on Subclinical Hypothyroidism with Special Reference to the Serum Lipid Pattern, Acta Medica Scandinavica, 10.1111/j.0954-6820.1976.tb08197.x, 200:1-6, (63-67) Stamler J (1975) Diet-Related Risk Factors for Human Atherosclerosis: Hyperlipidemia, Hypertension, Hyperglycemia — Current Status Diet and Atherosclerosis, 10.1007/978-1-4615-9029-3_9, (125-158), . Rosenman R and Friedman M (1974) Neurogenic Factors in Pathogenesis of Coronary Heart Disease, Medical Clinics of North America, 10.1016/S0025-7125(16)32158-7, 58:2, (269-279), Online publication date: 1-Mar-1974. Keen H (2007) Glucose tolerance, plasma lipids and atherosclerosis, Proceedings of the Nutrition Society, 10.1079/PNS19720061, 31:3, (339-345), Online publication date: 1-Dec-1972. Horwitz C, Krut L and Kaminsky L (1972) Some properties of particles of egg-yolk phosphatidylcholine and cholesterol, Chemistry and Physics of Lipids, 10.1016/0009-3084(72)90047-3, 8:3, (185-198), Online publication date: 1-Apr-1972. Hall Y, Stamler J, Cohen D, Mojonnier L, Epstein M, Berkson D, Whipple I and Catchings S (1972) Effectiveness of a low saturated fat, low cholesterol, weight-reducing diet for the control of hypertriglycer-idemia, Atherosclerosis, 10.1016/0021-9150(72)90086-X, 16:3, (389-403), Online publication date: 1-Nov-1972. Lees R and Wilson D (1971) The Treatment of Hyperlipidemia, New England Journal of Medicine, 10.1056/NEJM197101282840406, 284:4, (186-195), Online publication date: 28-Jan-1971. Horwitz C, Krut L and Kaminsky L (1971) Cholesterol uptake by egg-yolk phosphatidylcholine, Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 10.1016/0005-2760(71)90178-0, 239:2, (329-336), Online publication date: 1-Jul-1971. Hauss W (1970) Über Entstehung und Verhütung der Arteriosklerose Über Entstehung und Verhütung der Arteriosklerose. Ätiologie und Pathogenese der Silikose sowie ihre kausale Beeinflussung, 10.1007/978-3-322-98813-3_1, (7-33), . Frantz I and Moore R (1969) The sterol hypothesis in atherogenesis, The American Journal of Medicine, 10.1016/0002-9343(69)90020-5, 46:5, (684-690), Online publication date: 1-May-1969. Bacon G and Parkhurst R (1969) Metabolic Considerations in the Treatment of Juvenile Diabetes Mellitus, Medical Clinics of North America, 10.1016/S0025-7125(16)32708-0, 53:6, (1367-1378), Online publication date: 1-Nov-1969. Stamler J, Berkson D, Levinson M, Mojonnier L, Epstein M, Hall Y, Burkey F, Soyugenc R and Andelman S (1968) A LONG-TERM CORONARY PREVENTION EVALUATION PROGRAM, Annals of the New York Academy of Sciences, 10.1111/j.1749-6632.1968.tb53853.x, 149:2 Atheroscleros, (1022-1037), Online publication date: 1-Nov-1968. Shields L, Kipfer R, Sansoy O and Gellenthien C (2016) Serum Lipids in Spanish- and Anglo-American Men, Angiology, 10.1177/000331976701800804, 18:8, (484-497), Online publication date: 1-Aug-1967. McGandy R, Hegsted D and Stare F (1967) Dietary Fats, Carbohydrates and Atherosclerotic Vascular Disease, New England Journal of Medicine, 10.1056/NEJM196707272770405, 277:4, (186-192), Online publication date: 27-Jul-1967. (2009) References, Acta Medica Scandinavica, 10.1111/j.0954-6820.1966.tb02415.x, 179:S446, (42-44) Sidd J, Sasahara A and Littmann D (1966) Coronary-Artery Disease in Identical Twins, New England Journal of Medicine, 10.1056/NEJM196601132740201, 274:2, (55-60), Online publication date: 13-Jan-1966. Brown D, Kinch S and Doyle J (1966) Fasting and postprandial serum triglyceride levels in health and in ischemic heart disease, Journal of Atherosclerosis Research, 10.1016/S0368-1319(66)80004-2, 6:3, (232-239), Online publication date: 1-May-1966. Mills G, Taylaur C and Wilkinson P (1966) The equivalence of biochemical aids to the prognosis of cardiovascular disease, Clinica Chimica Acta, 10.1016/0009-8981(66)90249-X, 13:4, (527-529), Online publication date: 1-Apr-1966. SCANU A (1965) Factors Affecting Lipoprotein Metabolism1 1This work was supported by grants from the Public Health Service (HE 08727-01) and from the Chicago and Illinois Heart Associations.2 2Literature published after June 30, 1964, is not included in this survey. , 10.1016/B978-1-4831-9939-9.50009-7, (63-138), . Haan D and Tilsner V (2016) The Influence of Anticoagulants on Angina Pectoris, Angiology, 10.1177/000331976501600108, 16:1, (49-52), Online publication date: 1-Jan-1965. LITTLE J, SHANOFF H, ROE R, CSIMA A and YANO R (1965) Studies of Male Survivors of Myocardial Infarction, Circulation, 10.1161/01.CIR.31.6.854, 31:6, (854-862), Online publication date: 1-Jun-1965. Ogston D and McAndrew G (1965) Relationship between the blood levels of cholesterol, mucoproteins, and fibrinogen in ischaemic heart disease, Journal of Clinical Pathology, 10.1136/jcp.18.2.175, 18:2, (175-177), Online publication date: 1-Mar-1965. Glatzel H (1964) Fettverzehr-Plasmacholesterin-Koronarkrankheit, Archiv für Kreislaufforschung, 10.1007/BF02120037, 43:4, (249-296), Online publication date: 1-May-1964. FISCHER R and USAMC C (1963) Its Relation to Obesity and the Military Diet: Serum Cholesterol in a Military Population, Journal of the American Dietetic Association, 10.1016/S0002-8223(21)18987-4, 42:6, (511-517), Online publication date: 1-Jun-1963. Marek Z, Jaegermann K and Ciba T (1962) Atherosclerosis and levels of serum cholesterol in postmortem investigations, American Heart Journal, 10.1016/0002-8703(62)90063-7, 63:6, (768-774), Online publication date: 1-Jun-1962. MCDONOUGH J, HAMES C, GREENBERG B, GRIFFIN L and EDWARDS A (1962) Observations on Serum Cholesterol Levels in the Twin Population of Evans County, Georgia, Circulation, 10.1161/01.CIR.25.6.962, 25:6, (962-969), Online publication date: 1-Jun-1962. Steinberg D (1962) Chemotherapeutic Approaches to the Problem of Hyperlipidemia , 10.1016/S1054-3589(08)60508-6, (59-159), . Brunner D, Altman S, Loebl K and Schwartz S (1962) a-Cholesterol percentages in coronary patients with and without increased total serum cholesterol levels and in healthy controls, Journal of Atherosclerosis Research, 10.1016/S0368-1319(62)80014-3, 2:6, (424-437), Online publication date: 1-Nov-1962. Tochowicz L, Pasyk S and Denikiewicz W (1962) Cholesterol and serum turbidity evaluation measurements in atherosclerosis, American Heart Journal, 10.1016/0002-8703(62)90062-5, 63:6, (760-767), Online publication date: 1-Jun-1962. (1962) Triglycerides and Ischemic Heart Disease, New England Journal of Medicine, 10.1056/NEJM196203082661016, 266:10, (521-521), Online publication date: 8-Mar-1962. KEYS A (1961) Editorial , Circulation, 23:6, (805-812), Online publication date: 1-Jun-1961. Brown W (1961) THE RELIABILITY OF METHODS FOR CHOLESTEROL DETERMINATION IN STUDIES ON CORONARY DISEASE, Medical Journal of Australia, 10.5694/j.1326-5377.1961.tb69695.x, 2:12, (467-470), Online publication date: 1-Sep-1961. KAUNITZ H (1961) Re-Evaluation of Some Factors in Arteriosclerosis, Nature, 10.1038/192009a0, 192:4797, (9-12), Online publication date: 1-Oct-1961. (1961) Bibliography Coronary Vasodilators, 10.1016/B978-0-08-009371-0.50011-9, (151-202), . Pezold F (1961) Die Lipoproteide des Blutserums und ihre klinische Bedeutung Sechsundsechzigster Kongress, 10.1007/978-3-642-96027-7_48, (427-449), . Hames C and Greenberg B (1961) A Comparative Study of Serum Cholesterol Levels in School Children and Their Possible Relation to Atherogenesis, American Journal of Public Health and the Nations Health, 10.2105/AJPH.51.3.374, 51:3, (374-385), Online publication date: 1-Mar-1961. Bennhold H and Ott H (1961) Der Stofftransport Hilfsmechanismen des Stoffwechsels I, 10.1007/978-3-642-94824-4_4, (166-275), . WURM M, KOSITCHEK R and STRAUS R (1960) Lipoproteins Quantitated by Paper Electrophoresis as an Index of Atherosclerosis, Circulation, 21:4, (526-537), Online publication date: 1-Apr-1960.PETERSON J, WILCOX A, HALEY M and KEITH R (1960) Hourly Variation in Total Serum Cholesterol, Circulation, 22:2, (247-253), Online publication date: 1-Aug-1960. Rivin A and Wong H (1960) Lipid measurements in coronary artery disease, The American Journal of Cardiology, 10.1016/0002-9149(60)90057-6, 5:6, (784-788), Online publication date: 1-Jun-1960. LINDGREN F and NICHOLS A (1960) Structure and Function of Human Serum Lipoproteins The Plasma Proteins, 10.1016/B978-0-12-395720-7.50008-0, (1-58), . Scarborough W, Smith E and Baker B (1960) Studies on subjects with and without coronary heart disease. Serum lipid, lipoprotein, and protein determinations and their relation to ballistocardiographic findings (a preliminary survey), American Heart Journal, 10.1016/0002-8703(60)90381-1, 59:1, (19-35), Online publication date: 1-Jan-1960. Carlson L (2009) Serum Lipids in Men with Myocardial Infarction, Acta Medica Scandinavica, 10.1111/j.0954-6820.1960.tb03562.x, 167:6, (399-413) Schimert G, Schimmler W, Schwalb H and Eberl J (1960) Die Coronarerkrankungen. Coronarinsuffizienz, Angina pectoris und Herzinfarkt Angeborene Herz- und Gefässmissbildungen Durchblutungsstörungen des Herzmuskels, 10.1007/978-3-642-94790-2_3, (653-1712), . Williams J (1960) Selected Subjects in Sedimentation Analysis, with Some Applications to Biochemistry Fortschritte der Chemie organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products / Progrés Dans la Chimie des Substances Organiques Naturelles, 10.1007/978-3-7091-7159-2_8, (434-502), . SCHLESSINGER B, WILSON F and MILCH L (1959) Serum Parameters as Discriminators between Normal and Coronary Groups, Circulation, 19:2, (265-268), Online publication date: 1-Feb-1959.GRUNDY S and GRIFFIN A (1959) Effects of Periodic Mental Stress on Serum Cholesterol Levels, Circulation, 19:4, (496-498), Online publication date: 1-Apr-1959.PAGE I and LEWIS L (1959) Lipoproteins, Cholesterol and Serum Proteins as Predictors of Myocardial Infarction, Circulation, 20:6, (1011-1027), Online publication date: 1-Dec-1959. Smith E, de Alvarez R and Forsander J (1959) Serum protein, lipid, and lipoprotein fractions in normal human pregnancy, American Journal of Obstetrics and Gynecology, 10.1016/0002-9378(59)90235-2, 77:2, (326-334), Online publication date: 1-Feb-1959. Olson R (1959) I. Cardiovascular Disease—With Particular Attention to Atherosclerosis, American Journal of Public Health and the Nations Health, 10.2105/AJPH.49.9.1120, 49:9, (1120-1128), Online publication date: 1-Sep-1959. Ralli E (2016) Nutritional Disturbances Associated With Diabetes Mellitus, Postgraduate Medicine, 10.1080/00325481.1959.11712676, 26:5, (612-616), Online publication date: 1-Nov-1959. Lin T and Chen K (1959) Cholesterol and Its Relation to Atherosclerosis Fortschritte der Arzneimittelforschung / Progress in Drug Research / Progrès des recherches pharmaceutiques, 10.1007/978-3-0348-7035-1_2, (127-158), . Beaumont J and Lenègre J (1959) Vitamin A tolerance test and fat metabolism disorders in angina pectoris, American Heart Journal, 10.1016/0002-8703(59)90333-3, 58:2, (163-170), Online publication date: 1-Aug-1959. Portman O (2016) Dietary Factors and the Serum Cholesterol Level, Postgraduate Medicine, 10.1080/00325481.1959.11712608, 26:3, (386-391), Online publication date: 1-Sep-1959. Anderson Z (1959) Current Dietary Recommendations for the Prevention and Treatment of Coronary Heart Disease and What They Mean to the Dairy Industry, Journal of Dairy Science, 10.3168/jds.S0022-0302(59)90753-2, 42:8, (1401-1409), Online publication date: 1-Aug-1959. Ofner F and O'Connell T (1959) SERUM CHOLESTEROL LEVELS IN THE AGED, Medical Journal of Australia, 10.5694/j.1326-5377.1959.tb59037.x, 1:11, (355-356), Online publication date: 1-Mar-1959. Brock J (2008) Research in Clinical Nutrition Ciba Foundation Symposium - Significant Trends in Medical Research, 10.1002/9780470719176.ch12, (243-272) SPRAGUE H (1958) Editorial , Circulation, 17:1, (1-4), Online publication date: 1-Jan-1958.DAY A, WILKINSON G and Peters J (1958) Clearing Factor Inhibitor in Human Atherosclerosis, Circulation, 18:1, (76-81), Online publication date: 1-Jul-1958. Adlersberg D and Sobotka H (1958) PATHOLOGICAL MANIFESTATIONS OF ABNORMAL CHOLESTEROL METABOLISM Cholesterol, 10.1016/B978-1-4832-2772-6.50015-2, (375-425), . Furman R, Howard R, Norcia L and Keaty E (1958) The influence of androgens, estrogens and related steroids on serum lipids and lipoproteins, The American Journal of Medicine, 10.1016/0002-9343(58)90364-4, 24:1, (80-97), Online publication date: 1-Jan-1958. Weinhouse S (2015) CELLULAR MECHANISM OF METABOLISM, Journal of the American Geriatrics Society, 10.1111/j.1532-5415.1958.tb00705.x, 6:3, (182-189), Online publication date: 1-Mar-1958. Pohndorf R (2013) Cholesterol Studies: A Review, Research Quarterly. American Association for Health, Physical Education and Recreation, 10.1080/10671188.1958.10612980, 29:2, (180-192), Online publication date: 1-May-1958. FURMAN R, HOWARD R, SHETLAR M, KEATY E and IMAGAWA R (1958) A Comparison of the Serum Lipids, Lipoproteins, Glycoproteins, Urinary 17-Ketosteroids, and Gonadotropins in Eunuchs and Control Male Subjects, Circulation, 10.1161/01.CIR.17.6.1076, 17:6, (1076-1085), Online publication date: 1-Jun-1958. Gofman J (1958) Diet in the prevention and treatment of myocardial infarction, The American Journal of Cardiology, 10.1016/0002-9149(58)90058-4, 1:2, (271-283), Online publication date: 1-Feb-1958. Iglauer A (2016) Medical Management of Peripheral Vascular Disease, Angiology, 10.1177/000331975800900103, 9:1, (11-14), Online publication date: 1-Feb-1958. Hauss W (1958) Pathophysiologische Probleme bei Coronardurchblutungsstörungen Probleme der Coronardurchblutung, 10.1007/978-3-642-99862-1_14, (199-214), . PAGE I, STARE F, CORCORAN A, POLLACK H and WILKINSON C (1957) Atherosclerosis and the Fat Content of the Diet, Circulation, 16:2, (163-178), Online publication date: 1-Aug-1957.MAINLAND D (1957) Safety in Numbers, Circulation, 16:5, (784-790), Online publication date: 1-Nov-1957. Fischer F (1957) Die Lipcproteine des Serums bei Gesunden und Atherosklerosekranken, Klinische Wochenschrift, 10.1007/BF01480789, 35:8, (373-380), Online publication date: 1-Apr-1957. Schettler G, Dietrich F, Eggstein M and Jobst H (1957) Zur Bestimmung der Serumlipoproteide mit der Zonenelektrophorese im Stärkemedium, Klinische Wochenschrift, 10.1007/BF01482156, 35:6, (268-275), Online publication date: 1-Mar-1957. Van Itallie T (1957) Dietary Constituents and Atherosclerosis, Journal of the American Dietetic Association, 10.1016/S0002-8223(21)16594-0, 33:4, (352-357), Online publication date: 1-Apr-1957. Olson R (1957) Role of Dietary Fat in Human Nutrition, American Journal of Public Health and the Nations Health, 10.2105/AJPH.47.12.1537, 47:12, (1537-1541), Online publication date: 1-Dec-1957. Doyle J, DeLalla L, Baker W, Heslin A and Brown R (1957) Serum lipoproteins in preclinical and in manifest ischemic heart disease, Journal of Chronic Diseases, 10.1016/0021-9681(57)90060-7, 6:1, (33-45), Online publication date: 1-Jul-1957. Ofner F (1957) SERUM CHOLESTEROL LEVELS IN THE AGED, Medical Journal of Australia, 10.5694/j.1326-5377.1957.tb60420.x, 2:24, (856-858), Online publication date: 1-Dec-1957. Thomas G, Wann L, Allam A, Thompson R, Michalik D, Sutherland M, Sutherland J, Lombardi G, Watson L, Cox S, Valladolid C, Abd el-Maksoud G, Al-Tohamy Soliman M, Badr I, El-Halim Nur el-din A, Clarke E, Thomas I, Miyamoto M, Kaplan H, Frohlich B, Narula J, Stewart A, Zink A and Finch C (2014) Why Did Ancient People Have Atherosclerosis? From Autopsies to Computed Tomography to Potential Causes, Global Heart, 10.1016/j.gheart.2014.04.002, 9:2, (229) October 1, 1956Vol 14, Issue 4 Advertisement Article InformationMetrics © 1956 American Heart Association, Inc.https://doi.org/10.1161/01.CIR.14.4.689 Originally publishedOctober 1, 1956 PDF download Advertisement