精子发生
情感(语言学)
血睾丸屏障
纳米颗粒
细胞生物学
化学
支持细胞
生物物理学
男科
生物
医学
纳米技术
心理学
材料科学
沟通
出处
期刊:Nanomedicine
[Future Medicine]
日期:2012-04-01
卷期号:7 (4): 579-596
被引量:136
摘要
Due to the widespread use of nanomaterials in medical, industrial and military applications, the question as to whether nanoparticles (NPs) cause harmful disturbances in human health, especially on the reproductive system, remains a matter of concern. In this review, we focus mainly on the in vivo and in vitro effects of NPs on spermatogenesis at the clinical, cellular and molecular levels. In general, most NPs display adverse effects on spermatogenesis at these various levels; but, some NPs show no adverse effects. However, the mechanism underlying NP disruption of spermatogenesis and penetration of the blood-testis barrier remains unclear. In this review, we raise many hypotheses for experimental testing in order to elucidate the mechanism.
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