Self-priming arrest by modified random oligonucleotides facilitates the quality control of whole genome amplification

[1,2], is widelyused in forensic analyses but also extends its applica-tion to pathology, molecular diagnostics, and environ-mental microbiology. Recently, two new methods forWGA have been introduced. The Wrst is based onstrand displacement synthesis [3] and termed multiple-displacement ampliWcation. It uses the highly proces-sive