壳聚糖
抗菌活性
银纳米粒子
化学
白色念珠菌
大肠杆菌
金黄色葡萄球菌
微生物学
细胞毒性
粘质沙雷氏菌
发酵乳杆菌
体外
细菌
核化学
纳米颗粒
生物
生物化学
材料科学
纳米技术
乳酸
遗传学
基因
植物乳杆菌
作者
Hoang Vinh Tran,Тран Дай Лам,Cham Thi Ba,Vũ Đình Hoàng,Ngoc Thinh Nguyen,Dien Gia Pham,Phuc Xuan Nguyen
标识
DOI:10.1016/j.colsurfa.2010.02.007
摘要
Silver nanoparticles (AgNPs) have been known to have inhibitory and bactericidal effects. In this paper we investigated: (i) the synthesis and kinetics of finely dispersed AgNPs in a biocompatible chitosan-derived polysaccharide solution; (ii) the antibacterial activities toward both gram− (Escherichia coli and Pseudomonas aeruginosa) and gram+ bacteria (Lactobacillus fermentum, Staphylococcus aureus and Baciilus subtilis) and yeast (Candida albicans) of the obtained AgNPs; and (iii) in vitro cytotoxicity against HepG2 (hepatocellular carcinoma), Lu (human lung carcinoma), KB (human epidermic carcinoma), MCF-7 (human breast carcinoma) cancer cell lines. The samples demonstrated considerably high antibacterial and antiproliferative activities against above bacterial strains and cell lines, which can be explained on the basis of finely and homogenously dispersed nanoparticles.
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