C-reactive protein and the acute phase response

A conference 'C-reactive protein and the plasma protein response to tissue injury' was held at the Barbizon-Plaza Hotel, New York, 21-23 September 1981. The proceedings wilI be published in Anrzah qf g/w ,%'w Ybrk Acade, O' qf Niencey, 1982. reed from its ability to precipitate the somatic C polysaccharide of pneumococci. Among the other acute phase proteins are a number of proteinase inhibitors, coagulation, complement and transport proteins and some proteins, like CRP, whose normal functions are unknown. One of these, serum arnyloid A protein (SAA), is of particular interest because it seems to be the precursor of amyloid A (AA) protein. Amyloidosis is a rare but serious complication of those chronic inflammatory diseases characterized by a sustained acute phase response and high SAA levels. Amyloid fibrils tbrmed of AA are C~mld. on p. 28 Cornplement research