Coincidence of Bladder and Prostate Cancer

No AccessJournal of UrologyClinical Urology: Original Article1 Jan 1997Coincidence of Bladder and Prostate Cancer Thomas Y. Chun Thomas Y. ChunThomas Y. Chun View All Author Informationhttps://doi.org/10.1016/S0022-5347(01)65281-9AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Diagnostic bias can be a problem when determining the coincidence of prostate and bladder cancer. The objective of this study was to calculate the coincidence of bladder and prostate cancer after correcting for diagnostic bias. Materials and Methods: The cancer registry at 1 medical institution provided the number of patients diagnosed with prostate or bladder cancer between 1989 and 1994. The expected incidences of bladder and prostate cancer were calculated using 1987 to 1991 Surveillance, Epidemiology and End Results data. Diagnostic bias was determined by reviewing the charts of all patients with both types of cancer. Results: Of 100 patients with a diagnosis of bladder cancer 25 (25%) also had prostate cancer and 25 of 651 (3.8%) with prostate cancer also had bladder cancer. Diagnostic bias was involved in diagnosing bladder cancer in 3 of 25 patients and prostate cancer in 7 of 25. When these patients are eliminated from the incidence data, the rate of prostate cancer in those with bladder cancer is 17% and the rate of bladder cancer in those patients with prostate cancer is 3.2%. In an age, sex and race matched general population the expected rates of prostate and bladder cancer were 0.9 and 0.18%, respectively. Conclusions: The rate of bladder cancer in patients with prostate cancer is 18 times higher (p <0.01) and the rate of prostate cancer in those with bladder cancer is 19 times higher (p <0.01) than expected. These rates do not include cases involving diagnostic bias. References 1 : Multiple unrelated primary malignancies of the genitourinary tract.. J. Urol.1957; 77: 96. Abstract, Google Scholar 2 : Multiple primary neoplasms in association with prostate cancer in black and white patients.. Cancer1987; 59: 380. Google Scholar 3 : Incidental carcinoma of the prostate: a review of the literature and critical reappraisal of classification.. J. Urol.1980; 124: 626. Abstract, Google Scholar 4 : Prostatic involvement in bladder cancer. Prostate mapping in 20 cystoprostatectomy specimens.. Cancer1986; 58: 2096. Google Scholar 5 : SEER Cancer Statistics Review, 1973-1991: Tables and Graphs. Bethesda, Maryland: National Cancer Institute1994. Google Scholar 6 : Unsuspected bladder carcinoma in patients undergoing radical prostatectomy.. J. Urol.1994; 152: 397. Abstract, Google Scholar 7 : Simultaneous presentation of adenocarcinoma of prostate and transitional cell carcinoma of bladder.. Urology1991; 37: 202. Google Scholar 8 : Coincident vesical transitional cell carcinoma and prostatic carcinoma: clinical features and treatment.. Brit. J. Urol.1986; 58: 153. Google Scholar 9 : Coexisting adenocarcinoma of prostate in patients undergoing cystoprostatectomy for bladder cancer.. Urology1987; 30: 100. Google Scholar 10 : Unsuspected prostatic adenocarcinoma in patients who have undergone radical cystoprostatectomy for transitional cell carcinoma of the bladder.. J. Urol.1988; 139: 1214. Abstract, Google Scholar 11 : Adenocarcinoma of the prostate in cystoprostatectomy specimens removed for bladder cancer.. Cancer1989; 63: 381. Google Scholar 12 : Management of patients with concurrent primary tumors of bladder and prostate.. Urology1983; 21: 562. Google Scholar 13 : Molecular and immunologic approaches in the management of bladder cancer.. Urol. Clin. N. Amer.1991; 18: 515. Google Scholar 14 : Molecular biology of prostate cancer: oncogenes and tumor suppressor genes. In: Prostate Cancer. Edited by . New York: Wiley-Liss, Inc.1994: 19. chapt. 2. Google Scholar Department of Urology, New York University Medical Center, New York, New York.© 1997 by American Urological Association, Inc.FiguresReferencesRelatedDetailsCited byInaba H, Kimura T, Onuma H, Sato S, Kido M, Yamamoto T, Fukuda Y, Takahashi H and Egawa S (2020) Tumor Location and Pathological Features of Latent and Incidental Prostate Cancer in Contemporary Japanese MenJournal of Urology, VOL. 204, NO. 2, (267-272), Online publication date: 1-Aug-2020.Reesink D, Fransen van de Putte E, Vegt E, De Jong J, van Werkhoven E, Mertens L, Bex A, van der Poel H, van Rhijn B, Horenblas S and Meijer R (2015) Clinical Relevance of Incidental Prostatic Lesions on FDG-Positron Emission Tomography/Computerized Tomography—Should Patients Receive Further Evaluation?Journal of Urology, VOL. 195, NO. 4 Part 1, (907-912), Online publication date: 1-Apr-2016.Singh A, Kinoshita Y, Rovito P, Landas S, Silberstein J, Nsouli I, Wang C and Haas G (2018) Higher Than Expected Association of Clinical Prostate and Bladder CancersJournal of Urology, VOL. 179, NO. 5S, (S2-S5), Online publication date: 1-May-2008.Boorjian S, Cowan J, Konety B, DuChane J, Tewari A, Carroll P and Kane C (2018) Bladder Cancer Incidence and Risk Factors in Men With Prostate Cancer: Results From Cancer of the Prostate Strategic Urologic Research EndeavorJournal of Urology, VOL. 177, NO. 3, (883-888), Online publication date: 1-Mar-2007.Shah S, Lui P, Baldwin D and Ruckle H (2018) Urothelial Carcinoma After External Beam Radiation Therapy for Prostate CancerJournal of Urology, VOL. 175, NO. 6, (2063-2066), Online publication date: 1-Jun-2006.LANGENSTROER P, CARROLL P and THRASHER J (2018) CLINICAL AND PATHOLOGICAL CHARACTERISTICS OF UNSTAGEABLE PROSTATE CANCER: ANALYSIS OF THE CaPSURE™ DATABASEJournal of Urology, VOL. 174, NO. 1, (118-120), Online publication date: 1-Jul-2005.SINGH A, KINOSHITA Y, ROVITO P, LANDAS S, SILBERSTEIN J, NSOULI I, WANG C and HAAS G (2018) HIGHER THAN EXPECTED ASSOCIATION OF CLINICAL PROSTATE AND BLADDER CANCERSJournal of Urology, VOL. 173, NO. 5, (1526-1529), Online publication date: 1-May-2005.HAUTMANN S, CONRAD S, HENKE R, ERBERSDOBLER A, SIMON J, STRAUB M, GRAEFEN M, HAUTMANN R and HULAND H (2018) DETECTION RATE OF HISTOLOGICALLY INSIGNIFICANT PROSTATE CANCER WITH SYSTEMATIC SEXTANT BIOPSIES AND FINE NEEDLE ASPIRATION CYTOLOGYJournal of Urology, VOL. 163, NO. 6, (1734-1738), Online publication date: 1-Jun-2000.JOHNSTONE P, POWELL C, RIFFENBURGH R, ROHDE D and KANE C (2018) SECOND PRIMARY MALIGNANCIES IN T1-3N0 PROSTATE CANCER PATIENTS TREATED WITH RADIATION THERAPY WITH 10-YEAR FOLLOWUPJournal of Urology, VOL. 159, NO. 3, (946-949), Online publication date: 1-Mar-1998. Volume 157Issue 1January 1997Page: 65-67 Advertisement Copyright & Permissions© 1997 by American Urological Association, Inc.MetricsAuthor Information Thomas Y. Chun More articles by this author Expand All Advertisement PDF downloadLoading ...