已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Pressure-Controlled vs Volume-Controlled Ventilation in Acute Respiratory Failure

医学 通风(建筑) 概化理论 机械通风 重症监护医学 呼吸分钟容积 呼吸功 心脏病学 麻醉 内科学 呼吸系统 工程类 机械工程 统计 数学
作者
Nuttapol Rittayamai,Christina M. Katsios,François Beloncle,Jan O. Friedrich,Jordi Mancebo,Laurent Brochard
出处
期刊:Chest [Elsevier]
卷期号:148 (2): 340-355 被引量:114
标识
DOI:10.1378/chest.14-3169
摘要

BACKGROUND

Mechanical ventilation is a cornerstone in the management of acute respiratory failure. Both volume-targeted and pressure-targeted ventilations are used, the latter modes being increasingly used. We provide a narrative review of the physiologic principles of these two types of breath delivery, performed a literature search, and analyzed published comparisons between modes.

METHODS

We performed a systematic review and meta-analysis to determine whether pressure control-continuous mandatory ventilation (PC-CMV) or pressure control-inverse ratio ventilation (PC-IRV) has demonstrated advantages over volume control-continuous mandatory ventilation (VC-CMV). The Cochrane tool for risk of bias was used for methodologic quality. We also introduced physiologic criteria as quality indicators for selecting the studies. Outcomes included compliance, gas exchange, hemodynamics, work of breathing, and clinical outcomes. Analyses were completed with RevMan5 using random effects models.

RESULTS

Thirty-four studies met inclusion criteria, many being at high risk of bias. Comparisons of PC-CMV/PC-IRV and VC-CMV did not show any difference for compliance or gas exchange, even when looking at PC-IRV. Calculating the oxygenation index suggested a poorer effect for PC-IRV. There was no difference between modes in terms of hemodynamics, work of breathing, or clinical outcomes.

CONCLUSIONS

The two modes have different working principles but clinical available data do not suggest any difference in the outcomes. We included all identified trials, enhancing generalizability, and attempted to include only sufficient quality physiologic studies. However, included trials were small and varied considerably in quality. These data should help to open the choice of ventilation of patients with acute respiratory failure.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
XJY完成签到,获得积分10
3秒前
4秒前
5秒前
科研通AI2S应助Ricardo采纳,获得10
7秒前
PUTIDAXIAN发布了新的文献求助10
8秒前
seeeee发布了新的文献求助10
9秒前
大意的绿蓉完成签到,获得积分10
10秒前
沉静妙之完成签到 ,获得积分10
13秒前
英俊的铭应助称心的以菱采纳,获得10
13秒前
不找了完成签到,获得积分10
16秒前
16秒前
NexusExplorer应助summer夏采纳,获得10
19秒前
kk完成签到,获得积分10
21秒前
小松鼠发布了新的文献求助20
25秒前
顾矜应助Zing采纳,获得10
25秒前
香蕉觅云应助顺顺利利采纳,获得10
27秒前
YUE发布了新的文献求助10
28秒前
LSH完成签到 ,获得积分10
29秒前
29秒前
白鸽应助吃人陈采纳,获得10
31秒前
思源应助banimadao采纳,获得10
31秒前
qian72133发布了新的文献求助30
32秒前
立恒儿完成签到,获得积分10
34秒前
34秒前
35秒前
35秒前
hhuajw发布了新的文献求助10
36秒前
乐乐应助Pluto采纳,获得10
36秒前
36秒前
38秒前
骨小梁发布了新的文献求助10
39秒前
40秒前
41秒前
奋斗若冰发布了新的文献求助100
42秒前
summer夏发布了新的文献求助10
42秒前
Lex完成签到 ,获得积分10
42秒前
Ttttt发布了新的文献求助10
42秒前
KINDMAGIC发布了新的文献求助10
43秒前
46秒前
yxyer发布了新的文献求助30
46秒前
高分求助中
Sustainability in Tides Chemistry 2800
The Young builders of New china : the visit of the delegation of the WFDY to the Chinese People's Republic 1000
Rechtsphilosophie 1000
Bayesian Models of Cognition:Reverse Engineering the Mind 888
Le dégorgement réflexe des Acridiens 800
Defense against predation 800
XAFS for Everyone (2nd Edition) 600
热门求助领域 (近24小时)
化学 医学 生物 材料科学 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 基因 遗传学 催化作用 物理化学 免疫学 量子力学 细胞生物学
热门帖子
关注 科研通微信公众号,转发送积分 3133652
求助须知:如何正确求助?哪些是违规求助? 2784626
关于积分的说明 7767874
捐赠科研通 2439828
什么是DOI,文献DOI怎么找? 1297069
科研通“疑难数据库(出版商)”最低求助积分说明 624840
版权声明 600791