Preface About the authors Definitions and Units of Symbols Equations Introduction 1. Clearance 2. Volume of Distribution 3. Half-life 4. How Drugs are Cleared by the Liver 5. Bioavailability and First-Pass Clearance 6. Predicting Drug Interactions and the Effects of Disease States for Metabolised Drugs 7. Clearance of Drugs by the Kidneys 8. Drug Protein Binding 9. Non-Linear Pharmacokinetics 10. How to Determine the Pharmacokinetic Parameters of a Drug 11. Pharmacodynamics-the Concentration-Effect Relationship 12. Designing Dose Regimens 13. Therapeutics Drug Monitoring Answers