Feline Pemphigus Foliaceus

Feline pemphigus foliaceus is an uncommon skin disorder in cats but still the most common autoimmune skin disorder seen in this species. It is a crusting dermatosis involving the ears, head, paws, and ungual folds primarily. Although cytology is helpful in supporting a diagnosis, biopsy of pustules or crusts for histopathology is required for a definitive diagnosis. Therapy has evolved over the years as we have learned more about the different ways cats respond to drugs and as new drugs became available. Most cats will respond to proper therapy, although it may be needed long term for control.