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Computational Characterization of Flow and Hemolytic Performance of the UltraMag Blood Pump for Circulatory Support

循环系统 血流 连续流动 流量(数学) 表征(材料科学) 计算机科学 医学 心脏病学 工程类 材料科学 机械 生化工程 纳米技术 物理
作者
M. Ertan Taskin,Katharine Fraser,Tao Zhang,Barry Gellman,Andi Fleischli,Kurt A. Dasse,Bartley P. Griffith,Zhongjun J. Wu
出处
期刊:Artificial Organs [Wiley]
卷期号:34 (12): 1099-1113 被引量:85
标识
DOI:10.1111/j.1525-1594.2010.01017.x
摘要

The Levitronix UltraMag blood pump is a next generation, magnetically suspended centrifugal pump and is designed to provide circulatory support for pediatric and adult patients. The aim of this study is to investigate the hemodynamic and hemolytic characteristics of this pump using the computational fluid dynamics (CFD) approach. The computational domain for CFD analysis was constructed from the three-dimensional geometry (3D) of the UltraMag blood pump and meshed into 3D tetrahedral/hybrid elements. The governing equations of fluid flow were computationally solved to obtain a blood flow through the blood pump. Further, hemolytic blood damage was calculated by solving a scalar transport equation where the scalar variable and the source term were obtained utilizing an empirical power-law correlation between the fluid dynamic variables and hemolysis. To obtain mesh independent flow solution, a comparative examination of vector fields, hydrodynamic performance, and hemolysis predictions were carried out. Different sizes of tetrahedral and tetrahedral/hexahedral mixed hybrid models were considered. The mesh independent solutions were obtained by a hybrid model. Laminar and SST κ-ω turbulence flow models were used for different operating conditions. In order to pinpoint the most significant hemolytic region, the flow field analysis was coupled to the hemolysis predictions. In summary, computational characterization of the device was satisfactorily carried out within the targeted operating conditions of the device, and it was observed that the UltraMag blood pump can be safely operated for its intended use to create a circulatory support for both pediatric and adult-sized patients.

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