神经化学
铁
癫痫
感觉运动皮层
皮质(解剖学)
铁质
化学
神经科学
内科学
麻醉
医学
心理学
无机化学
有机化学
作者
L. James Willmore,G W Sypert,John B. Munson,R.W. Hurd
出处
期刊:Science
[American Association for the Advancement of Science (AAAS)]
日期:1978-06-30
卷期号:200 (4349): 1501-1503
被引量:272
标识
DOI:10.1126/science.96527
摘要
A single injection of 5 or 10 microliters of ferrous or ferric chloride into rat or cat sensorimotor cortex resulted in chronic recurrent focal paroxysmal electroencephalographic discharges as well as behavioral convulsions and electrical seizures. Recurrent focal epileptiform discharge caused by cortical injection of iron salts suggests that the development of human posttraumatic epilepsy may depend, in part, on the neurochemical alterations induced by the principal metallic ions found in whole blood.
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