内科学
脂联素
内分泌学
瘦素
体质指数
胰岛素抵抗
脂肪组织
肥胖
脂肪细胞
胰岛素
医学
脂肪因子
化学
作者
Mayumi Matsubara,Shuichiro Maruoka,Shinji Katayose
出处
期刊:European journal of endocrinology
[Bioscientifica]
日期:2002-08-01
卷期号:: 173-180
被引量:505
标识
DOI:10.1530/eje.0.1470173
摘要
Adiponectin, a novel adipocyte-derived collagen-like protein, is the gene product of the adipose most-abundant gene transcript 1 (apM1), which has been considered to have anti-inflammatory and anti-atherogenic effects.To characterize the relationship between adiponectin and leptin, the ob gene product, in normal-weight and obese women.In this cross-sectional study, we measured fasting plasma adiponectin by ELISA, leptin concentrations by RIA, and related parameters such as blood pressure, body mass index (BMI), body fat mass, lipids, fasting blood glucose and insulin in 353 non-diabetic adult women with a wide range of BMI values.Plasma adiponectin concentrations in women with the highest tertile of BMI (at least 25.0 kg/m(2)) were decreased compared with those in the middle (22.0-25.0 kg/m(2)) or lowest (
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