The Global, Regional, and National Burden of Psoriasis: Results and Insights From the Global Burden of Disease 2019 Study

医学 银屑病 疾病负担 入射(几何) 疾病负担 人口学 全球卫生 疾病 潜在生命损失数年 医疗保健 老年学 人口 环境卫生 公共卫生 内科学 病理 物理 皮肤病科 社会学 预期寿命 光学 经济 经济增长
作者
Giovanni Damiani,Nicola Luigi Bragazzi,C. Karimkhani Aksut,Dongze Wu,Gianfranco Alicandro,Dennis McGonagle,Cui Guo,Robert P. Dellavalle,Ayman Grada,Priscilla Wong,Carlo La Vecchia,Lai‐Shan Tam,Kevin D. Cooper,Mohsen Naghavi
出处
期刊:Frontiers in Medicine [Frontiers Media]
卷期号:8 被引量:146
标识
DOI:10.3389/fmed.2021.743180
摘要

Background: Psoriasis is a common, chronic, inflammatory, debilitating, systemic disease with a great impact on healthcare systems worldwide. As targeted therapies have transformed the therapeutic landscape, updated estimates of the Global Burden of Disease (GBD) imposed by psoriasis are necessary in order to evaluate the effects of past health care policies and to orient and inform new national and international healthcare strategies. Methods: Data were extracted from the GBD 2019 study, which collates a systematic review of relevant scientific literature, national surveys, claims data, and primary care sources on the prevalence of psoriasis. Prevalence data were combined with disability weight (DW) to yield years lived with disability (YLDs). Measures of burden at global, regional, and national levels were generated for incidence, prevalence, and YLDs, due to psoriatic disease. All measures were reported as absolute numbers, percentages, and crude and age-adjusted rates per 100,000 persons. In addition, psoriasis burden was assessed by socio-demographic index (SDI). Findings: According to the GBD 2019 methodology, there were 4,622,594 (95% uncertainty interval or UI 4,458,904-4,780,771) incident cases of psoriasis worldwide in 2019. The age-standardized incidence rate in 2019 was 57.8 (95% UI 55.8-59.7) per 100,000 people. With respect to 1990, this corresponded to a decrease of 20.0% (95% UI -20.2 to -19.8). By sex, the age-standardized incidence rate was similar between men [57.8 (95% UI 55.8-59.8) per 100,000 people] and women [(57.8 (95% UI 55.8-59.7) per 100,000 people]. With respect to 1990, this corresponded to a decrease by 19.5% (95% UI -19.8 to -19.2) and by 20.4% (95% UI -20.7 to -20.2) for men and women, respectively. The age-standardized incidence rate per 100,000 persons was found to vary widely across geographic locations. Regionally, high-income countries and territories had the highest age-standardized incidence rate of psoriasis [112.6 (95% UI 108.9-116.1)], followed by high-middle SDI countries [69.4 (95% UI 67.1-71.9)], while low SDI countries reported the lowest rate [38.1 (95% UI 36.8-39.5)]. Similar trends were detected for prevalence and YLDs. Conclusion: In general, psoriasis burden is greatest in the age group of 60-69 years, with a relatively similar burden among men and women. The burden is disproportionately greater in high-income and high SDI index countries of North America and Europe. With advances in psoriasis therapeutics, objective evaluation of psoriasis disease burden is critical to track the progress at the population level.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
zj完成签到,获得积分10
刚刚
蓝橙完成签到,获得积分10
1秒前
5秒前
GD88完成签到,获得积分10
6秒前
糟糕的梨愁完成签到,获得积分10
7秒前
莫西莫西完成签到 ,获得积分10
8秒前
小趴蔡完成签到 ,获得积分10
10秒前
唐唐发布了新的文献求助10
10秒前
飘逸剑身完成签到,获得积分10
13秒前
airtermis完成签到 ,获得积分10
13秒前
gfasdjsjdsjd完成签到,获得积分10
14秒前
14秒前
杨宁完成签到 ,获得积分10
14秒前
MchemG应助transition采纳,获得20
15秒前
科研通AI2S应助科研通管家采纳,获得10
16秒前
lxy发布了新的文献求助10
18秒前
gfasdjsjdsjd发布了新的文献求助10
19秒前
JCao727完成签到,获得积分10
19秒前
19秒前
20秒前
OAHCIL完成签到 ,获得积分10
21秒前
lixueao发布了新的文献求助10
22秒前
无辜的行云完成签到 ,获得积分0
25秒前
FIN应助gfasdjsjdsjd采纳,获得20
27秒前
今后应助gfasdjsjdsjd采纳,获得10
27秒前
排骨炖豆角完成签到 ,获得积分10
29秒前
一叶知秋应助大橙子采纳,获得10
31秒前
kk完成签到,获得积分10
34秒前
敏感春天完成签到,获得积分10
34秒前
凶狠的期待完成签到,获得积分10
36秒前
自然函发布了新的文献求助30
36秒前
JF123_完成签到 ,获得积分10
37秒前
量子星尘发布了新的文献求助10
37秒前
39秒前
杨召发布了新的文献求助10
40秒前
didi完成签到,获得积分10
40秒前
keyby发布了新的文献求助10
42秒前
FashionBoy应助xdc采纳,获得10
47秒前
杨召完成签到,获得积分10
52秒前
大橙子发布了新的文献求助10
56秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Handbook of Industrial Diamonds.Vol2 1100
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038128
求助须知:如何正确求助?哪些是违规求助? 3575831
关于积分的说明 11373827
捐赠科研通 3305610
什么是DOI,文献DOI怎么找? 1819255
邀请新用户注册赠送积分活动 892655
科研通“疑难数据库(出版商)”最低求助积分说明 815022