Research progress on two component system of bacteria.

Bacteria needs complex and accurate signal transduction system to adapt to the changes in cellular and environment.Two component systems are abundant in prokaryotes,which consist of a histidine kinase(HK) and a response regulator(RR).They regulate cellular signal transduction pathway,according to phosphorylation and dephosphorylation.This review mainly introduces the progress made in structure,mechanism and function research,and explores the role of two component systems in cell signal transduction.