Phenolic, Megastigmane, Nucleotide, Acetophenon and Monoterpene Glycosides from Phlomis samia and P. carica

Phytochemical investigations on the aerial parts of Phlomis samia resulted in the isolation of a simple phenolic glucoside, 2,6-dimethoxy-4-hydroxyphenol-1-O-b -D-glucopyranoside (1); a megastigmane glucoside, phlomuroside (=3-hydroxy-5,6-epoxy-b -ionol-9-O-b -D-glucopyranoside) (2); and a nucleotide glycoside, uridine (3). From the aerial parts of P. carica, the same phenolic glucoside, 2,6-dimethoxy-4-hydroxyphenol-1-O-b -D-glucopyranoside (1); as well as an acetophenon glucoside, picein (4); and 2 monoterpenoid glucosides, - betulalbuside A (5) and 1-hydroxylinaloyl-6-O-b -D-glucopyranoside (6) - were isolated and identified. The structure elucidation of the isolates was based on spectroscopic evidence.