Construction of fully substituted carbon centers containing a heteroatom and a CF3 group via in situ generated p-quinone methides

Facile and practical construction of heteroatom as well as CF₃-containing fully substituted carbon centers was realized by 1,6-conjugate additions of a variety of heteronucleophiles to in situ generated δ-CF₃-δ-substituted p-quinone methides.