Reliability Criteria of Two-Dimensional Shear Wave Elastography: Analysis of 4277 Measurements in 788 Patients

医学 肝硬化 弹性成像 肝纤维化 瞬态弹性成像 肝活检 接收机工作特性 内科学 核医学 放射科 活检 超声波
作者
Anita Pathil,Sylvain Lemoine,Christophe Cassinotto,Victor de Lédinghen,Maxime Ronot,Marie Irlès‐Depé,Valérie Vilgrain,Brigitte Le Bail,Valérie Paradis,Clémence M. Canivet,Sophie Michalak,Marie‐Christine Rousselet,Pierre‐Emmanuel Rautou,J. Lebigot,Gilles Hunault,Anne Crouan,Christophe Aubé,Jérôme Boursier
出处
期刊:Clinical Gastroenterology and Hepatology [Elsevier BV]
卷期号:20 (2): 400-408.e10 被引量:12
标识
DOI:10.1016/j.cgh.2020.12.013
摘要

Two-dimensional shear wave elastography (2D-SWE) is an accurate method for the non-invasive evaluation of liver fibrosis. We aimed to determine the reliability criteria and the number of necessary reliable measurements for 2D-SWE.788 patients with chronic liver disease underwent liver biopsy and 2D-SWE examination in three centers. The 4277 2D-SWE measurements performed were 2:1 randomly divided into derivation (n = 2851) and validation (n = 1426) sets. Reliability criteria for a 2D-SWE measurement were defined in the derivation set from the intrinsic characteristics given by the device (mean liver stiffness, standard deviation, diameter of the region of interest), with further evaluation in the validation set.In the whole population of 4277 measurements, AUROC for bridging fibrosis was 0.825 ± 0.006 and AUROC for cirrhosis was 0.880 ± 0.006. Mean stiffness and coefficient of variation (CV) were independent predictors of bridging fibrosis or cirrhosis. From these two parameters, new criteria were derived to define a reliable 2D-SWE measurement: stiffness <8.8 kPa, or stiffness between 8.8-11.9 kPa with CV <0.25, or stiffness ≥12.0 kPa with CV <0.10. In the validation set, AUROC for bridging fibrosis was 0.830 ± 0.013 in reliable measurements vs 0.667 ± 0.031 in unreliable measurements (P < .001). AUROC for cirrhosis was 0.918±0.014 vs 0.714 ± 0.027, respectively (P < .001). The best diagnostic accuracy for a 2D-SWE examination was achieved from three reliable measurements.Reliability of a 2D-SWE measurement relies on the coefficient of variation and the liver stiffness level. A 2D-SWE examination should include three reliable measurements according to our new criteria.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
1111完成签到,获得积分10
2秒前
hjy发布了新的文献求助10
2秒前
李健应助天边采纳,获得10
2秒前
橘橙色发布了新的文献求助10
3秒前
竹马子完成签到,获得积分10
5秒前
完美世界应助超帅冬易采纳,获得10
5秒前
聪明摩托发布了新的文献求助10
6秒前
8秒前
腼腆的绝山完成签到,获得积分20
9秒前
堪归完成签到 ,获得积分10
10秒前
11秒前
maox1aoxin应助橘橙色采纳,获得30
12秒前
SYLH应助yuan采纳,获得30
12秒前
超帅冬易完成签到,获得积分10
15秒前
fan发布了新的文献求助10
17秒前
大力云朵发布了新的文献求助10
18秒前
1111发布了新的文献求助10
22秒前
想胖的竹竿完成签到,获得积分10
22秒前
传奇3应助ylq采纳,获得10
23秒前
25秒前
26秒前
FashionBoy应助呵呵采纳,获得10
27秒前
Chloe发布了新的文献求助10
28秒前
arlon完成签到,获得积分10
29秒前
iW完成签到 ,获得积分10
30秒前
白潇潇发布了新的文献求助10
30秒前
123完成签到,获得积分10
30秒前
杨枝甘露加雪糕完成签到,获得积分10
31秒前
32秒前
35秒前
别闹闹完成签到 ,获得积分10
35秒前
一个靓仔完成签到 ,获得积分10
36秒前
江夏清发布了新的文献求助10
36秒前
CC发布了新的文献求助10
37秒前
欢喜幻桃发布了新的文献求助10
39秒前
39秒前
40秒前
练习时长两年半应助hjy采纳,获得10
40秒前
40秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3975658
求助须知:如何正确求助?哪些是违规求助? 3519986
关于积分的说明 11200481
捐赠科研通 3256410
什么是DOI,文献DOI怎么找? 1798247
邀请新用户注册赠送积分活动 877490
科研通“疑难数据库(出版商)”最低求助积分说明 806376