Machine learning for predictive data analytics in medicine: A review illustrated by cardiovascular and nuclear medicine examples

The evidence-based medicine allows the physician to evaluate the risk-benefit ratio of a treatment through setting and data. Risk-based choices can be done by the doctor using different information. With the emergence of new technologies, a large amount of data is recorded offering interesting perspectives with machine learning for predictive data analytics. Machine learning is an ensemble of methods that process data to model a learning problem. Supervised machine learning algorithms consist in using annotated data to construct the model. This category allows to solve prediction data analytics problems. In this paper, we detail the use of supervised machine learning algorithms for predictive data analytics problems in medicine. In the medical field, data can be split into two categories: medical images and other data. For brevity, our review deals with any kind of medical data excluding images. In this article, we offer a discussion around four supervised machine learning approaches: information-based, similarity-based, probability-based and error-based approaches. Each method is illustrated with detailed cardiovascular and nuclear medicine examples. Our review shows that model ensemble (ME) and support vector machine (SVM) methods are the most popular. SVM, ME and artificial neural networks often lead to better results than those given by other algorithms. In the coming years, more studies, more data, more tools and more methods will, for sure, be proposed.