心脏毒性
医学
细胞毒性T细胞
免疫检查点
广谱
PD-L1
程序性细胞死亡1
癌症研究
免疫系统
化疗
内科学
免疫疗法
免疫学
生物
化学
生物化学
体外
组合化学
标识
DOI:10.33696/cancerimmunol.2.022
摘要
Immune checkpoint inhibitors (ICIs) are a new type of broad-spectrum antitumor drugs, which mainly include cytotoxic T-lymphocyte-associated protein-4 (CTLA-4) inhibitors, programmed cell death protein-1 (PD-1) and its ligand PD-L1 inhibitors. Since 2011, ICIs have been approved for more than 20 kinds of malignant tumors.
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