The Personalized Precise Exercise Training with Holistic Integrative Protocol (PPET‐HIP) for Effective Management in Patient with Chronic Diseases (CDs)

BACKGROUND The patients with chronic diseases (CDs, i.e. hypertension, hyperglycemia, hyperlipidemia, hyperuricemia and obesity etc. with or without MI or Stoke) were uncured, according to the guidelines of all each one group of exports. However, based on our new Holistic Integrative Physiology and Medicine (HIPM), we might be able to use the core personalized precise exercise training and continuous functional monitoring with holistic integrative protocol ( PPET‐HIP) for effective management of CDs patients. METHODS Ten CDs patients, who has more than 10–30year history and four of them had MI or Stoke, were recruited from 2014–2018.Before and after 12‐week intervention, general evaluations(blood pressure, glucose, and lipid profiles), cardiopulmonary exercise testing (CPET), echocardiogram, and the adjustment of drugs treated CDs patients were recorded respectively. Based on HIPM for CPET interpretation, we gave each patient an PPET‐HIP for adjusting of all life styles. RESULTS All patients exercised safely with any problem. After 12w HIPM‐PPT management, the all abnormal parameters of hypertensive, hyperglycemia, hyperlipidemia, hyperuricemia and obesity were become normal; CPET parameters, left ventricular function, and QoL were improved significantly than those before ( P <0.05). Then we decreased drugs dosages and totally stopped drugs, the levels of blood pressure, glucose and lipid were still maintained stable. Surprisingly, the curable condition was achieved in CDs patients. CONCLUSIONS HIPM guiding CPET for the PPET‐HIP could safely and effectively control the conditions of patients with CDs. Support or Funding Information National Natural Science Foundation of China (81470204); Fuwai Hospital, National Cardiovascular Institute of Chinese Academy of Medical Sciences (2012‐YJR02); Research on Clinical Characteristics of the Capital (Z141107002514084); Research and Outcome Promotion of Clinical Characteristics in the Capital (Project No. Z161100000516127)