Mortality Trends of Idiopathic Pulmonary Fibrosis in the United States From 2004 Through 2017

医学 特发性肺纤维化 肺纤维化 纤维化 内科学
作者
Niranjan Jeganathan,Rory A. Smith,Matheni Sathananthan
出处
期刊:Chest [Elsevier BV]
卷期号:159 (1): 228-238 被引量:40
标识
DOI:10.1016/j.chest.2020.08.016
摘要

Background The burden of idiopathic pulmonary fibrosis (IPF)-related mortality in the United States in recent years is not well characterized. Research Question What are the trends in IPF-related mortality rates in the United States from 2004 through 2017? Study Design and Methods We used the Multiple Cause of Death Database available through the Centers for Disease Control and Prevention website, which contains data from all deceased US residents. IPF-related deaths were identified using International Classification of Diseases, 10th revision, codes. We examined annual trends in age-adjusted mortality rates stratified by age, sex, race, and state of residence. We also evaluated trends in place of death and underlying cause of death. Results From 2004 through 2017, the age-adjusted mortality decreased by 4.1% in men (from 75.5 deaths/1,000,000 in 2004 to 72.4 deaths/1,000,000 in 2017) and by 13.4% in women (from 46.3 deaths/1,000,000 in 2004 to 40.1 deaths/1,000,000 in 2017). This overall decrease was driven mainly by a decline in IPF-related mortality in patients younger than 85 years. The decreasing trend also was noted in all races except White men, in whom the rate remained stable. The most common cause of death was pulmonary fibrosis. The percentage of deaths occurring in the inpatient setting and nursing homes decreased, whereas the percentage of deaths occurring at home and hospice increased. Interpretation From 2004 through 2017, the IPF age-adjusted mortality rates decreased. This may be explained partly by a decline in smoking in the United States, but further research is needed to evaluate other environmental and genetic contributors. The burden of idiopathic pulmonary fibrosis (IPF)-related mortality in the United States in recent years is not well characterized. What are the trends in IPF-related mortality rates in the United States from 2004 through 2017? We used the Multiple Cause of Death Database available through the Centers for Disease Control and Prevention website, which contains data from all deceased US residents. IPF-related deaths were identified using International Classification of Diseases, 10th revision, codes. We examined annual trends in age-adjusted mortality rates stratified by age, sex, race, and state of residence. We also evaluated trends in place of death and underlying cause of death. From 2004 through 2017, the age-adjusted mortality decreased by 4.1% in men (from 75.5 deaths/1,000,000 in 2004 to 72.4 deaths/1,000,000 in 2017) and by 13.4% in women (from 46.3 deaths/1,000,000 in 2004 to 40.1 deaths/1,000,000 in 2017). This overall decrease was driven mainly by a decline in IPF-related mortality in patients younger than 85 years. The decreasing trend also was noted in all races except White men, in whom the rate remained stable. The most common cause of death was pulmonary fibrosis. The percentage of deaths occurring in the inpatient setting and nursing homes decreased, whereas the percentage of deaths occurring at home and hospice increased. From 2004 through 2017, the IPF age-adjusted mortality rates decreased. This may be explained partly by a decline in smoking in the United States, but further research is needed to evaluate other environmental and genetic contributors. The Promise (and Pitfalls) of Administrative Data for Idiopathic Pulmonary FibrosisCHESTVol. 159Issue 1PreviewReliable and current population-based estimates of idiopathic pulmonary fibrosis (IPF) mortality are needed to better understand the epidemiologic trends of IPF. This knowledge is key to informing IPF-related health policy, patient advocacy, and future research planning. Full-Text PDF
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
2秒前
2秒前
2秒前
4秒前
Owen应助晒太阳的加菲猫采纳,获得10
5秒前
anna发布了新的文献求助10
7秒前
7秒前
wu基督教发布了新的文献求助10
8秒前
9秒前
余南发布了新的文献求助10
10秒前
晒太阳的加菲猫完成签到,获得积分10
10秒前
笑点低诗桃完成签到,获得积分20
11秒前
泡泡脑瓜完成签到,获得积分10
11秒前
13秒前
liche发布了新的文献求助10
13秒前
14秒前
修管子发布了新的文献求助10
14秒前
15秒前
共享精神应助gx采纳,获得10
15秒前
高手完成签到,获得积分20
16秒前
无所谓的啦完成签到,获得积分10
16秒前
ylq关闭了ylq文献求助
17秒前
wu基督教完成签到,获得积分20
17秒前
18秒前
迷人的芹菜完成签到,获得积分10
18秒前
19秒前
Miracle发布了新的文献求助10
19秒前
高手发布了新的文献求助10
20秒前
20秒前
我啊完成签到 ,获得积分10
23秒前
slp发布了新的文献求助30
24秒前
24秒前
gx发布了新的文献求助10
26秒前
英姑应助笑点低诗桃采纳,获得10
28秒前
youwenjing11发布了新的文献求助10
28秒前
王铂然发布了新的文献求助10
31秒前
大模型应助GGBOND采纳,获得10
32秒前
脑洞疼应助gx采纳,获得10
32秒前
Eunice完成签到,获得积分10
33秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989115
求助须知:如何正确求助?哪些是违规求助? 3531367
关于积分的说明 11253688
捐赠科研通 3269986
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882078
科研通“疑难数据库(出版商)”最低求助积分说明 809105