医学
便秘
益生元
膨胀
功能性便秘
重症监护医学
慢性便秘
梅德林
随机对照试验
合生元
内科学
益生菌
腹泻
细菌
政治学
法学
生物
遗传学
作者
Maliha Naseer,Shiva Poola,Süleyman Uraz,Veysel Tahan
出处
期刊:Current Clinical Pharmacology
[Bentham Science]
日期:2020-12-15
卷期号:15 (3): 207-215
被引量:21
标识
DOI:10.2174/1574884715666200212125035
摘要
Constipation is a highly prevalent functional gastrointestinal disorder that may significantly affect the quality of life and health care costs. Treatment for constipation has been broadly reviewed by cognitive therapies, medications, and surgical interventions. Gut microbiota such as Bifidobacterium, Clostridium, Bacteroidetes, and Lactobacilli have been demonstrated in functional gastrointestinal disorders and prebiotics to play a role in augmenting their presence. Prebiotics are ingredients in foods that remain undigested, stimulating the bacteria. There are a variety of prebiotics; however, there exists only a handful of studies that describe their efficacy for chronic constipation. The purpose of this study is to review the available literature on the utility of different commercially available prebiotics in patients with functional and chronic idiopathic constipation. To fulfil the objectives of the study, published articles in the English language on databases such as Pubmed, Ovid Medline, and EMBASE were searched. The terms prebiotics, constipation, chronic constipation, functional constipation were used. We reviewed and included 21 randomized controlled trials exploring the role of prebiotics in constipated adults. Prebiotics are effective treatments for chronic idiopathic constipation and showed improvement in the stool consistency, number of bowel moments and bloating. Although which prebiotic formulary would promote improved symptoms of constipation is still not clear.
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