苯拉唑马布
医学
慢性阻塞性肺病
肺病
内科学
单克隆抗体
单克隆
重症监护医学
免疫学
抗体
嗜酸性粒细胞
哮喘
美波利祖马布
作者
Gerard J. Criner,Bartolomé R. Celli,Christopher E. Brightling,Àlvar Agustí,Alberto Papi,Dave Singh,Don D. Sin,Claus Vogelmeier,Frank C. Sciurba,Mona Bafadhel,Vibeke Backer,Motokazu Kato,Alejandra Ramírez‐Venegas,Yu-Feng Wei,Leif Bjermer,Vivian H. Shih,Maria Jison,Sean O’Quinn,Natalya Makulova,Paul Newbold
标识
DOI:10.1056/nejmoa1905248
摘要
Add-on benralizumab was not associated with a lower annualized rate of COPD exacerbations than placebo among patients with moderate to very severe COPD, a history of frequent moderate or severe exacerbations, and blood eosinophil counts of 220 per cubic millimeter or greater (Funded by AstraZeneca [GALATHEA and TERRANOVA] and Kyowa Hakko Kirin [GALATHEA]; GALATHEA and TERRANOVA ClinicalTrials.gov numbers, NCT02138916 and NCT02155660.).
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