已入深夜,您辛苦了!由于当前在线用户较少,发布求助请尽量完整地填写文献信息,科研通机器人24小时在线,伴您度过漫漫科研夜!祝你早点完成任务,早点休息,好梦!

Association of Habitual Preoperative Dietary Fiber Intake With Complications After Colorectal Cancer Surgery

医学 结直肠癌 四分位间距 内科学 队列研究 腹部外科 癌症 外科
作者
Dieuwertje E. Kok,Melissa Arron,Tess Huibregtse,Flip M. Kruyt,Dirk Jan Bac,Henk K. van Halteren,Ewout A. Kouwenhoven,Evertine Wesselink,Renate M. Winkels,Fränzel J.B. van Duijnhoven,Johannes H. W. de Wilt,Ellen Kampman
出处
期刊:JAMA Surgery [American Medical Association]
卷期号:156 (9): 827-827 被引量:8
标识
DOI:10.1001/jamasurg.2021.2311
摘要

Importance

Postoperative complications are associated with increased morbidity and mortality among patients with colorectal cancer. As a modifiable factor associated with gut health, dietary fiber intake is of interest with regard to the risk of complications after surgery for colorectal cancer.

Objective

To examine the association between preoperative dietary fiber intake and risk of complications after surgery for colorectal cancer.

Design, Setting, and Participants

This cohort study used data from the Colorectal Longitudinal, Observational Study on Nutritional and Lifestyle Factors (COLON) study, which recruited adult patients with colorectal cancer at any stage at diagnosis from 11 hospitals in the Netherlands between August 2010 and December 2017. The present study included patients with stage I to IV colorectal cancer who underwent elective abdominal surgery. Data were analyzed between December 2019 and September 2020.

Exposures

Habitual dietary fiber intake was assessed at diagnosis using a 204-item food frequency questionnaire.

Main Outcomes and Measures

Any complications, surgical complications, and anastomotic leakage occurring during the 30 days after surgery for colorectal cancer. The association between fiber intake and risk of postoperative complications was assessed using logistic regression analyses. Additional analyses stratified by sex, tumor location, and fiber source were performed.

Results

Among the 1399 patients included in the analysis, the median age at inclusion was 66 years (interquartile range, 61-72 years) and 896 (64%) were men. Any complications occurred in 397 patients (28%), and surgical complications occurred in 235 patients (17%). Of 1237 patients with an anastomosis, 67 (5%) experienced anastomotic leakage. Higher dietary fiber intake (per 10 g per day) was associated with a lower risk of any complications (odds ratio [OR], 0.75; 95% CI, 0.62-0.92) and surgical complications (OR, 0.76; 95% CI, 0.60-0.97), whereas no association with anastomotic leakage was found (OR, 0.97; 95% CI, 0.66-1.43). Among women, higher dietary intake was associated with any complications (OR, 0.64; 95% CI, 0.44-0.94), whereas there was no association among men (OR, 0.79; 95% CI, 0.63-1.01). Fiber intake from vegetables (per 1 g per day) was inversely associated with any (OR, 0.90; 95% CI, 0.83-0.99) and surgical (OR, 0.87; 95% CI, 0.78-0.97) complications.

Conclusions and Relevance

In this cohort study, higher habitual dietary fiber intake before surgery was associated with a lower risk of postoperative complications among patients with colorectal cancer. The findings suggest that improving preoperative dietary fiber intake may be considered in future prehabilitation programs for patients undergoing surgery for colorectal cancer.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
1秒前
11发布了新的文献求助10
2秒前
brwen完成签到,获得积分10
3秒前
9秒前
10秒前
互助棍哥完成签到,获得积分10
11秒前
一直向前发布了新的文献求助10
11秒前
钱小豪发布了新的文献求助10
16秒前
九日橙完成签到 ,获得积分10
16秒前
sci来完成签到,获得积分10
18秒前
20秒前
21秒前
赵一丁完成签到,获得积分10
21秒前
xy完成签到 ,获得积分10
22秒前
shame完成签到 ,获得积分10
23秒前
斯文代梅发布了新的文献求助10
25秒前
耐斯糖完成签到 ,获得积分10
28秒前
一直向前发布了新的文献求助10
28秒前
简单完成签到 ,获得积分10
31秒前
32秒前
zcg完成签到 ,获得积分10
34秒前
默默完成签到 ,获得积分10
34秒前
温柔的柠檬完成签到 ,获得积分10
38秒前
爱学习的YY完成签到 ,获得积分10
41秒前
JiayinLiu完成签到,获得积分20
42秒前
陈补天完成签到 ,获得积分10
46秒前
Shawn完成签到 ,获得积分10
46秒前
江南之南完成签到 ,获得积分10
47秒前
长安完成签到 ,获得积分10
47秒前
回来完成签到,获得积分10
50秒前
51秒前
斯文代梅完成签到,获得积分10
52秒前
辣椒完成签到 ,获得积分10
53秒前
Rondab应助科研通管家采纳,获得10
53秒前
Rondab应助科研通管家采纳,获得10
53秒前
54秒前
aa完成签到,获得积分10
57秒前
汉堡包应助水若琳采纳,获得10
58秒前
fanyueyue完成签到 ,获得积分10
1分钟前
4114完成签到,获得积分10
1分钟前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
Aktuelle Entwicklungen in der linguistischen Forschung 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989972
求助须知:如何正确求助?哪些是违规求助? 3532034
关于积分的说明 11256042
捐赠科研通 3270884
什么是DOI,文献DOI怎么找? 1805093
邀请新用户注册赠送积分活动 882256
科研通“疑难数据库(出版商)”最低求助积分说明 809216