生物分子
金属
组合化学
分子
配体(生物化学)
化学
氧化还原
纳米技术
催化作用
材料科学
有机化学
受体
生物化学
作者
Johannes Karges,Ryjul W. Stokes,Seth M. Cohen
标识
DOI:10.1016/j.trechm.2021.03.006
摘要
Metal complexes have been widely used for applications in the chemical and physical sciences due to their unique electronic and stereochemical properties. For decades the use of metal complexes for medicinal applications has been postulated and demonstrated. The distinct characteristics of metal complexes, including their molecular geometries (that are not readily accessed by organic molecules), as well as their ligand exchange, redox, catalytic, and photophysical reactions, give these compounds the potential to interact and react with biomolecules in unique ways and by distinct mechanisms of action. Herein, the potential of metal complexes to act as components bioactive therapeutic compounds is discussed.
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