化学
酮
胺化
光催化
醛
卤素
化学计量学
光化学
光敏剂
还原胺化
催化作用
组合化学
有机化学
光催化
烷基
作者
Zhonghua Qu,Xing Chen,Shuai Zhong,Guo‐Jun Deng,Huawen Huang
出处
期刊:Organic Letters
[American Chemical Society]
日期:2021-06-28
卷期号:23 (14): 5349-5353
被引量:46
标识
DOI:10.1021/acs.orglett.1c01654
摘要
A mild transition-metal- and photosensitizer-free photoredox system based on the combination of NaI and PPh3 was found to enable highly selective reduction of nitroarenes. This protocol tolerates a broad range of reducible functional groups such as halogen (Cl, Br, and even I), aldehyde, ketone, carboxyl, and cyano. Moreover, the photoredox catalysis with NaI and stoichiometric PPh3 provides also an alternative entry to Cadogan-type reductive amination when o-nitrobiarenes were used.
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