医学
自然科学
眼科
血管抑制剂
视力
糖尿病性视网膜病变
视网膜脱离
视网膜
贝伐单抗
黄斑水肿
浆液性液体
荧光血管造影
糖尿病性黄斑水肿
回顾性队列研究
作者
Nimet Yesim Ercalik,Serhat Imamoglu,Esra Turkseven Kumral,Nursal Melda Yenerel,Handan Bardak,Yavuz Bardak
标识
DOI:10.1080/15569527.2018.1459667
摘要
Purpose: The purpose of this study was to evaluate the influence of serous retinal detachment (SRD) on the outcome of intravitreal ranibizumab (IVR) therapy in diabetic macular oedema (DME).Materials and methods: Fifty-one eyes with cystoid macular oedema (CME) and SRD (study group) and 57 eyes with only CME (control group) that received pro re nata (PRN) IVR injections during a 6-month period were retrospectively evaluated. The outcome measures included changes in the central macular thickness (CMT) and best corrected visual acuity (BCVA) and injection numbers.Results: The mean initial CMT in the study and control groups was 467 ± 101 and 440 ± 89 µm, respectively. The mean BCVA in the study and control groups was 0.75 ± 0.38 and 0.59 ± 0.36 logarithm of minimal angle of resolution (LogMAR), respectively (p = 0.010). The study group received a mean of 2.2 ± 0.92 injections, whereas the control group received a mean of 2.54 ± 0.9 injections. The decrease in CMT was greater, but not significantly g...
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