医学
肝细胞癌
肝硬化
病毒性肝炎
肝病
酒精性肝炎
内科学
脂肪肝
丙型肝炎
酒精性肝病
肝炎
疾病
胃肠病学
作者
Harshad Devarbhavi,Sumeet K. Asrani,Juan Pablo Arab,Yvonne Ayerki Nartey,Elisa Pose,Patrick S. Kamath
标识
DOI:10.1016/j.jhep.2023.03.017
摘要
Liver disease accounts for two million deaths annually and is responsible for 4% of all deaths (1 out of every 25 deaths worldwide); approximately two-thirds of all liver-related deaths occur in men. Deaths are largely attributable to complications of cirrhosis and hepatocellular carcinoma, with acute hepatitis accounting for a smaller proportion of deaths. The most common causes of cirrhosis worldwide are related to viral hepatitis, alcohol, and non-alcoholic fatty liver disease. Hepatotropic viruses are the aetiological factor in most cases of acute hepatitis, but drug-induced liver injury increasingly accounts for a significant proportion of cases. This iteration of the global burden of liver disease is an update of the 2019 version and focuses mainly on areas where significant new information is available like alcohol-associated liver disease, non-alcoholic fatty liver disease, viral hepatitis, and hepatocellular carcinoma. We also devote a separate section to the burden of liver disease in Africa, an area of the world typically neglected in such documents.
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