Factors mediating pre-existing autism diagnosis and later suicidal thoughts and behaviors: A follow-up cohort study

自闭症 心理学 队列 发展心理学 临床心理学 队列研究 自杀行为 毒物控制 人为因素与人体工程学 医学 医疗急救 内科学 病理
作者
Jung-Chi Chang,Meng‐Chuan Lai,Shu‐Sen Chang,Susan Shur‐Fen Gau
出处
期刊:Autism [SAGE Publishing]
标识
DOI:10.1177/13623613231223626
摘要

Individuals diagnosed with autism spectrum disorder (ASD) are more likely to have suicidal thoughts and behaviors. However, little research delineates the temporal and mechanistic associations between potential risk factors and suicidality in autistic individuals. We assessed 129 autistic and 121 age-matched and sex-assigned-at-birth-matched typically developing (TD) children and youth at baseline and follow-up. We evaluated internalizing/externalizing problems, bullying experiences, and three executive function tasks at a mean baseline age of 13.4 years (standard deviation: 4.2 years). After an average of 5.8 years (standard deviation: 1.7 years), we evaluated their suicidal thoughts and behaviors. The experiences of being bullied partially mediated the temporal relationship between pre-existing ASD and later-reported suicidal thoughts. Several cognitive flexibility and sustained attention indices mediated the temporal relationship between pre-existing ASD and later-reported suicidal thoughts. A multiple mediation model confirmed that bullying victimization and cognitive flexibility jointly mediated the temporal relationship between ASD and suicidal thoughts. Better cognitive flexibility and experiences of bullying victimization in autistic children/youth were both associated with higher risks of later-reported suicidal thoughts in adolescence/adulthood. School bullying-prevention programs and tailored clinical support for autistic youth with better cognitive flexibility are warranted for personalized suicide prevention for the autistic population. Lay Abstract Autistic people are more likely to experience suicidal thoughts and behaviors. The underlying relationships between potential risk factors and suicidal thoughts and behaviors in autistic individuals remain unclear. To understand this, we investigated whether specific factors in childhood/youth explain the effects of pre-existing autism spectrum disorder (ASD) diagnoses on later suicidal thoughts and behaviors in adolescence/adulthood. We assessed internalizing and externalizing problems, bullying experiences, and executive functions (including cognitive flexibility, sustained attention, and spatial working memory) at an average baseline age of 13.4 years and suicidal thoughts and behaviors at an average follow-up age of 19.2 years among 129 autistic and 121 typically developing (TD) individuals. During the follow-up period in adolescence/adulthood, autistic individuals were more likely to report suicidal thoughts than TD individuals. Being bullied partially accounted for the relationship between a pre-existing ASD diagnosis and later-reported higher suicidal thoughts. Contrary to our hypothesis, higher (instead of lower) cognitive flexibility in some autistic young people appeared to partially explain their higher rates of suicidal thoughts compared with typically developing young people. The findings imply that school bullying prevention and tailored intervention programs for autistic people, especially those with higher cognitive flexibility, are warranted to reduce their risks of experiencing suicidal thoughts.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
油个大饼呜呜呜完成签到,获得积分10
1秒前
王哥完成签到,获得积分10
2秒前
诚心代芙完成签到 ,获得积分10
2秒前
2秒前
cowboy007发布了新的文献求助10
3秒前
乐乐应助eternity136采纳,获得10
4秒前
量子星尘发布了新的文献求助10
4秒前
5秒前
明眸完成签到 ,获得积分10
5秒前
6秒前
王手发布了新的文献求助10
7秒前
7秒前
7秒前
烟花应助zzq778采纳,获得10
9秒前
9秒前
欣欣发布了新的文献求助10
9秒前
小欣6116发布了新的文献求助10
10秒前
Jiuhui发布了新的文献求助10
10秒前
御风甜咖啡完成签到,获得积分10
10秒前
uupp完成签到,获得积分10
11秒前
机智雁凡完成签到,获得积分10
12秒前
Cheung2121发布了新的文献求助30
13秒前
14秒前
16秒前
谜记完成签到,获得积分10
16秒前
共享精神应助Cheung2121采纳,获得30
16秒前
光撒盐完成签到,获得积分10
17秒前
cowboy007完成签到,获得积分10
17秒前
张振宇完成签到 ,获得积分10
18秒前
zz发布了新的文献求助10
19秒前
zzq778发布了新的文献求助10
21秒前
黄怡婷完成签到 ,获得积分10
21秒前
Daisy应助科研通管家采纳,获得10
22秒前
机智苗应助科研通管家采纳,获得10
22秒前
香蕉觅云应助科研通管家采纳,获得10
22秒前
FashionBoy应助科研通管家采纳,获得10
22秒前
赘婿应助科研通管家采纳,获得10
22秒前
大模型应助科研通管家采纳,获得10
22秒前
yanmu2010应助科研通管家采纳,获得10
22秒前
kingwill应助科研通管家采纳,获得20
23秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038368
求助须知:如何正确求助?哪些是违规求助? 3576068
关于积分的说明 11374313
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029