At his first urological appointment, a 44-year-old male patient presented with gross hematuria and right lower back pain for one week. He had no history of smoking, occupational risks, trauma, urinary lithiasis, or any other comorbidities. The patient had no family history of malignancies. Laboratory tests revealed normal creatinine clearance, hemogram, coagulation tests, and negative urinary culture. Computed tomography imaging is shown in Figure 1. A diagnostic right ureteroscopy was performed, followed by a biopsy of the visible tumor and a double J stent placement.