Upfront necrosectomy for infected necrotising pancreatitis: a promising strategy?

Acute necrotising pancreatitis—a severe form of acute pancreatitis—can lead to acute necrotic fluid collections. The necrotic fluid collections can remain sterile or get infected, which is referred to as infected necrotising pancreatitis. Patients with acute pancreatitis who develop persistent organ failure (lasting >48 h) are classified as having severe acute pancreatitis.1 Organ failure and infected necrotising pancreatitis are the two major determinants of survival in acute pancreatitis.1 The initial management of acute pancreatitis is largely supportive, and no invasive intervention is recommended.