免疫系统
不利影响
队列
医学
回顾性队列研究
免疫学
肿瘤科
内科学
免疫疗法
作者
Guihong Wan,Wenxin Chen,Sara Khattab,Katie Roster,Nga Nguyen,Boshen Yan,Ahmad Rajeh,Jayhyun Seo,Hannah Rashdan,Leyre Zubiri,Matthew J. Hadfield,Shadmehr Demehri,Kun‐Hsing Yu,William Lotter,Alexander Gusev,Nicole R. LeBoeuf,Kerry L. Reynolds,Shawn G. Kwatra,Yevgeniy R. Semenov
出处
期刊:Lancet Oncology
[Elsevier BV]
日期:2024-07-15
卷期号:25 (8): 1053-1069
被引量:10
标识
DOI:10.1016/s1470-2045(24)00278-x
摘要
Understanding co-occurrence patterns and prognostic implications of immune-related adverse events is crucial for immunotherapy management. However, previous studies have been limited by sample size and generalisability. In this study, we leveraged a multi-institutional cohort and a population-level database to investigate co-occurrence patterns of and survival outcomes after multi-organ immune-related adverse events among recipients of immune checkpoint inhibitors.
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