碳酸酐酶
化学
生物化学
氧化还原
酶
碳酸
生物
无机化学
有机化学
作者
Yezhou Yu,Sally‐Ann Poulsen,Giovanna Di Trapani,Kathryn F. Tonissen
标识
DOI:10.1089/ars.2024.0693
摘要
Both redox and pH are important regulatory processes that underpin cell physiological functions, in addition to influencing cancer cell development and tumor progression. The thioredoxin (Trx) and glutathione redox systems and the carbonic anhydrase (CA) proteins are considered key regulators of cellular redox and pH, respectively, with components of the Trx system and CAs regarded as cancer therapeutic targets. However, the redox and pH axis in cancer cells is an underexplored topic of research.
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