间质细胞
生育率
间质细胞瘤
保持生育能力
医学
妇科
内科学
激素
促黄体激素
环境卫生
人口
作者
Paweł Miklis,Monika Rudzińska,Michał Sulewski
出处
期刊:Wiadomości lekarskie (Warsaw Poland)
[Foundation of Polish Physicians-Pro-Medica]
日期:2024-12-30
卷期号:77 (12): 2563-2565
摘要
Aim Even though Leydig cell tumor (LCT) represents the most common neoplasia among testicular sex cord–stromal tumors (SCSTs), it is a rare condition, comprising 1%‐2% of all testicular tumors, with a 10% risk of malignancy most commonly located in retroperitoneal lymph nodes. LCTs may demonstrate various clinical manifestations – from asymptomatic intratesticular swelling through nonspecific symptoms such as loss of libido, impotence or infertility, up to feminizing or virilizing syndromes due to hormonal activity of the tumor. This article presents a case of Leydig cell tumor that was associated with azoospermia what have rarely been reported worldwide. Material and methods does not concern Case report A 27-year-old male presented to the urologist with one-month history of palpable testicular mass. Imaging tests revealed a well demarcated solid focal lesion in the upper pole of the left testicle and semen analysis indicated azoospermia. Due to small testicular lesion, negative serum markers and negative reports for malignancy in MRI imaging, testis-sparing surgery (TSS) was performed. The final histopathological examination revealed a Leydig cells tumor positive for inhibin, calretinin and MelanA. Six month after the surgery spermatogenic function was partially restored what have rarely been reported in scientific papers. Summary This case indicates that TSS may provide an effective way of semen quality improvement, although further research is required.
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