TERT Gene Mutation in Gliomas Cross‐Linked With (NTRK, PDL1, ALK, IDH, P53, EGFR, HER2): A Integrative Review TERT Gene Mutation in Gliomas
医学
突变
基因
癌症研究
胶质瘤
基因突变
遗传学
生物
作者
Guilherme Augusto dos Santos,Guilherme Nobre Nogueira,Iasmin Maria Rodrigues Saldanha,Ana Gabriela Ponte Farias,Christine Mateus,Oliveiro Caetano de Freitas Neto,Maria Jânia Teixeira
Recent advancements in glioma treatment are largely driven by the identification of genetic alterations, which enhance diagnostic precision and prognostic assessments, and unveil potential therapeutic targets. TERT promoter mutations, in particular, are associated with a poorer prognosis and aggressive clinical behavior.