Clinical Phenotype and Disease Course of Inflammatory Bowel Disease in Iran: Results of the Iranian Registry of Crohn’s and Colitis (IRCC)

泛政治 医学 溃疡性结肠炎 内科学 炎症性肠病 胃肠病学 家族史 克罗恩病 疾病 流行病学 结直肠癌 结肠炎 病史 癌症 结肠镜检查
作者
Bahar Saberzadeh-Ardestani,Amir Ali Khosravi,Fariborz Mansour‐Ghanaei,Homayoon Vahedi,Nadieh Baniasadi,Mohammadreza Seyyedmajidi,Baran Parhizkar,Ahmad Hormati,Sayed Jalalledin Naghshbandi,Somaieh Matin,Amir Abbas Hassan Zadeh,Tarang Taghvaei,Mohsen Bahrami,Mandana Rafeey,Mitra Ahadi,Hassan Vossoughinia,Hashem Muosavi,Shahsanam Gheibi,Roya-Sadat Hosseini-Hemmatabadi,Abbas Yazdanbod,Saied Matinkhah,Farshad Sheikh Esmaeili,Hafez Fakheri,Seyed Hamid Moosavy,Iradj Maleki,Siavosh Nasseri‐Moghaddam,Bardia Khosravi,Fatemeh Farahmand,Mehri Najafi,Hosein Alimadadi,Masoud Malekzadeh,Amir Anushiravani,Amir Kasaeian,Sudabeh Alatab,Anahita Sadeghi,Amir Reza Radmard,Shadi Kolahdoozan,Zeynab Rajabi,Ali Reza Sima
出处
期刊:Archives of Iranian Medicine [Academy of Medical Sciences, I.R. Iran]
卷期号:27 (4): 183-190 被引量:1
标识
DOI:10.34172/aim.2024.27
摘要

Background: Data on the epidemiology of inflammatory bowel disease (IBD) in the Middle East are scarce. We aimed to describe the clinical phenotype, disease course, and medication usage of IBD cases from Iran in the Middle East. Methods: We conducted a cross-sectional study of registered IBD patients in the Iranian Registry of Crohn’s and Colitis (IRCC) from 2017 until 2022. We collected information on demographic characteristics, past medical history, family history, disease extent and location, extra-intestinal manifestations, IBD medications, and activity using the IBD-control-8 questionnaire and the Manitoba IBD index, admissions history, history of colon cancer, and IBD-related surgeries. Results: In total, 9746 patients with ulcerative colitis (UC) (n=7793), and Crohn’s disease (CD) (n=1953) were reported. The UC to CD ratio was 3.99. The median age at diagnosis was 29.2 (IQR: 22.6,37.6) and 27.6 (IQR: 20.6,37.6) for patients with UC and CD, respectively. The male-to-female ratio was 1.28 in CD patients. A positive family history was observed in 17.9% of UC patients. The majority of UC patients had pancolitis (47%). Ileocolonic involvement was the most common type of involvement in CD patients (43.7%), and the prevalence of stricturing behavior was 4.6%. A prevalence of 0.3% was observed for colorectal cancer among patients with UC. Moreover,15.2% of UC patients and 38.4% of CD patients had been treated with anti-tumor necrosis factor (anti-TNF). Conclusion: In this national registry-based study, there are significant differences in some clinical phenotypes such as the prevalence of extra-intestinal manifestations and treatment strategies such as biological use in different geographical locations.

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
2秒前
2秒前
端庄毛巾发布了新的文献求助30
2秒前
大模型应助MrRen采纳,获得10
4秒前
yukaiyuan发布了新的文献求助10
4秒前
polite完成签到 ,获得积分10
6秒前
毕蓝血完成签到 ,获得积分10
6秒前
lululala发布了新的文献求助10
7秒前
甜美的成败完成签到,获得积分10
7秒前
8秒前
研友_VZG7GZ应助我门牙有缝采纳,获得10
8秒前
8秒前
yalin完成签到,获得积分10
9秒前
12秒前
能干耳机发布了新的文献求助10
12秒前
13秒前
15秒前
15秒前
17秒前
bkagyin应助dd采纳,获得10
17秒前
SciGPT应助Seoyeong采纳,获得10
17秒前
wxy发布了新的文献求助10
18秒前
19秒前
imxiaobing发布了新的文献求助10
19秒前
XiaoMing完成签到,获得积分10
19秒前
Muhammad发布了新的文献求助10
20秒前
20秒前
21秒前
你看起来很好吃完成签到,获得积分10
21秒前
22秒前
23秒前
zyn完成签到,获得积分10
24秒前
嗯呐发布了新的文献求助10
24秒前
Chengcheng发布了新的文献求助30
24秒前
XiaoMing发布了新的文献求助10
25秒前
高大的冰双完成签到,获得积分10
26秒前
26秒前
tt完成签到,获得积分10
27秒前
wxy完成签到,获得积分10
27秒前
28秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 700
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
Nucleophilic substitution in azasydnone-modified dinitroanisoles 500
不知道标题是什么 500
Indomethacinのヒトにおける経皮吸収 400
Effective Learning and Mental Wellbeing 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3976126
求助须知:如何正确求助?哪些是违规求助? 3520340
关于积分的说明 11202586
捐赠科研通 3256847
什么是DOI,文献DOI怎么找? 1798509
邀请新用户注册赠送积分活动 877645
科研通“疑难数据库(出版商)”最低求助积分说明 806516