The Accelerated Aging Mouse Serves as a Model for Basic Research

With the global increase in the elderly population, research related to ageing has recently become one of the most important medical issues.In order to understand the mechanisms underlying the development of ageing and ageing-related diseases, animal models are essential for conducting relevant studies.Among these, mice have become one of the most commonly used models for ageing-related research due to their high similarity to humans, especially in terms of genetic makeup and physiological structure, short lifespan, and ease of reproduction.This review will discuss some of the common and emerging methods for establishing mouse ageing models, specifically focusing on accelerated mouse models developed in recent years.It will also include a list of general and specific ageing assays for reference in these studies.