Implications of the 2023-2024 MPXV Clade I Outbreak in the DRC to Global Public Health

Mpox, a zoonotic disease resulting from infection with monkeypox virus (MPXV), was previously considered endemic to central- and west Africa. However, an ongoing global outbreak of clade IIb (previously known as West African clade) MPXV associated with human-to-human transmission primarily through sexual contact has occurred since May 2022, with introduction of MPXV to regions and countries that had previously only reported sporadic imported cases [ 1 Thornhill J.P. et al. Monkeypox Virus Infection in Humans across 16 Countries - April-June 2022. N. Engl. J. Med. Jul. 2022; Crossref Scopus (1114) Google Scholar ], [ 2 Laurenson-Schafer H. et al. Description of the first global outbreak of mpox: an analysis of global surveillance data. Lancet Glob. Health. Jul. 2023; 11: e1012-e1023 Abstract Full Text Full Text PDF PubMed Scopus (0) Google Scholar ].