地平线
时间范围
医学
期限(时间)
心理干预
价值(数学)
预测值
透视图(图形)
精算学
成本效益分析
计量经济学
重症监护医学
统计
经济
计算机科学
数学
财务
内科学
精神科
物理
几何学
生物
人工智能
量子力学
生态学
作者
David D. Kim,Caroline R.M. Wilkinson,Elle Pope,James D. Chambers,Joshua T. Cohen,Peter J. Neumann
标识
DOI:10.1080/14737167.2017.1331432
摘要
Background: Debates persist on the appropriate time horizon from a payer’s perspective and how the time horizon in cost-effectiveness analysis (CEA) influences the value assessment.Methods: We systematically reviewed the Tufts Medical Center CEA Registry and identifiedUS-based studies that used a payer perspective from 2005–2014. We classified the identified CEAs as short-term (time horizon ≤ 5 years) and long-term (> 5 years), and examined associations between study characteristics and the specified time horizon. We also developed case studies with selected interventions to further explore the relationship between time horizon and projected costs, benefits, and incremental cost-effectiveness ratios (ICER).Results: Among 782 identified studies that met our inclusion criteria, 552 studies (71%) utilized a long-term time horizon while 198 studies (25%) used a short-term horizon. Among studies that employed multiple time horizons, the extension of the time horizon yielded more favorable ICERs in 19 cases and less favorable ICERs in 4 cases. Case studies showed the use of a longer time horizon also yielded more favorable ICERs.Conclusion: The assumed time horizon in CEAs can substantially influence the value assessment of medical interventions. To capture all consequences, we encourage the use of time horizons that extend sufficiently into the future.
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