Relationship between the consolidation to maximum tumor diameter ratio and outcomes following stereotactic body radiotherapy for stage I non-small-cell lung cancer

医学 肺癌 放射外科 阶段(地层学) 多元分析 核医学 放射治疗 内科学 古生物学 生物
作者
Yuichiro Tsurugai,Takuyo Kozuka,Naoki Ishizuka,Masahiko Oguchi
出处
期刊:Lung Cancer [Elsevier BV]
卷期号:92: 47-52 被引量:29
标识
DOI:10.1016/j.lungcan.2015.12.003
摘要

Purpose We investigated whether the ratio of the maximum diameter of consolidation to the maximum tumor diameter (consolidation/tumor ratio, CTR) predicted the outcomes of patients who received stereotactic body radiotherapy (SBRT) for non-small-cell lung cancer (NSCLC). Methods and materials Between 2005 and 2014, 237 patients with stage I NSCLC were treated with SBRT, receiving 48 Gy in 4 fractions. Of these patients, those who received pretreatment thin section computed tomography were selected for this analysis. The relationship between the CTR and outcomes (local control [LC], disease-free survival [DFS], and overall survival [OS]) was analyzed. Results One hundred and fifty-five patients were eligible. The median follow-up time was 34.7 months (range, 1.2–109.8). In the CTR < 0.5, CTR 0.5–<1, and CTR = 1 groups, 0, 2, and 12 patients experienced local recurrences, respectively. Three-year DFS and OS rates were 96.7% and 87.5% in the CTR < 0.5 group, 85.1% and 81.1% in the CTR 0.5–<1 group, and 63.3% and 70.1% in the CTR = 1 group, respectively. In multivariate analysis, CTR was the only significant predictor of DFS (P < 0.001). Conclusion The CTR effectively predicts DFS after SBRT in NSCLC patients.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
Zz发布了新的文献求助10
1秒前
gj发布了新的文献求助10
1秒前
猪猪hero发布了新的文献求助10
2秒前
感性的早晨完成签到,获得积分10
3秒前
Lucas应助忐忑的阑香采纳,获得10
4秒前
5秒前
周开心完成签到,获得积分10
7秒前
猪猪hero发布了新的文献求助10
7秒前
8秒前
12秒前
12秒前
JamesPei应助徐哈哈采纳,获得10
13秒前
猪猪hero发布了新的文献求助10
13秒前
thuuu完成签到,获得积分10
14秒前
gj完成签到,获得积分20
16秒前
香蕉妙菱发布了新的文献求助10
16秒前
YJ888发布了新的文献求助10
18秒前
cc完成签到,获得积分10
20秒前
Owen应助啦啦采纳,获得10
20秒前
猪猪hero发布了新的文献求助10
20秒前
量子星尘发布了新的文献求助80
21秒前
FashionBoy应助手可摘柠檬采纳,获得10
22秒前
村上种树完成签到,获得积分10
22秒前
CipherSage应助悄悄采纳,获得10
22秒前
nananaa应助诸葛烤鸭采纳,获得10
22秒前
22秒前
零零完成签到 ,获得积分10
29秒前
不学无术完成签到,获得积分10
31秒前
今后应助JUdy采纳,获得10
34秒前
深情安青应助hp采纳,获得10
35秒前
36秒前
英俊的铭应助Sunnyside采纳,获得10
37秒前
独特元蝶发布了新的文献求助10
39秒前
39秒前
猪猪hero发布了新的文献求助10
40秒前
潇湘雪月发布了新的文献求助10
40秒前
momo发布了新的文献求助10
41秒前
42秒前
42秒前
老实代曼完成签到,获得积分10
42秒前
高分求助中
A new approach to the extrapolation of accelerated life test data 1000
ACSM’s Guidelines for Exercise Testing and Prescription, 12th edition 500
‘Unruly’ Children: Historical Fieldnotes and Learning Morality in a Taiwan Village (New Departures in Anthropology) 400
Indomethacinのヒトにおける経皮吸収 400
Phylogenetic study of the order Polydesmida (Myriapoda: Diplopoda) 370
基于可调谐半导体激光吸收光谱技术泄漏气体检测系统的研究 350
Robot-supported joining of reinforcement textiles with one-sided sewing heads 320
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 3989242
求助须知:如何正确求助?哪些是违规求助? 3531393
关于积分的说明 11253753
捐赠科研通 3270010
什么是DOI,文献DOI怎么找? 1804868
邀请新用户注册赠送积分活动 882084
科研通“疑难数据库(出版商)”最低求助积分说明 809136