TEMPO-catalyzed Aerobic Oxygenation and Nitrogenation of Olefins via C═C Double-Bond Cleavage

A novel TEMPO-catalyzed aerobic oxygenation and nitrogenation of hydrocarbons via C═C double-bond cleavage has been disclosed. The reaction employs molecular oxygen as the terminal oxidant and oxygen-atom source by metal-free catalysis under mild conditions. This method can be used for the preparation of industrially and pharmaceutically important N- and O-containing motifs, directly from simple and readily available hydrocarbons.