Cerebroplacental ratio and aortic isthmus Doppler in early fetal growth restriction

医学 心脏病学 多普勒效应 内科学 前瞻性队列研究 舒张期 胎儿 脉动指数 多普勒成像 宫内生长受限 血流 血管阻力 血流动力学 怀孕 产科 血压 物理 天文 生物 遗传学
作者
Pratibha Choudhary,Amita Malik,Achla Batra
出处
期刊:Journal of Clinical Ultrasound [Wiley]
卷期号:49 (7): 754-761 被引量:4
标识
DOI:10.1002/jcu.23028
摘要

Abstract Purpose To assess the utility of cerebroplacental ratio (CPR) and fetal aortic isthmus (AoI) Doppler in the prediction of perinatal outcome in early fetal growth restriction (FGR). Methods A prospective observational cohort study of 70 early FGR cases was conducted through serial Doppler examinations and findings of the last examination were correlated with perinatal outcome. Doppler blood flow measurements of AoI included end diastolic velocity (EDV), peak systolic velocity (PSV), pulsatility index (PI), resistance index (RI), and isthmic flow index (IFI). Results Significant association of CPR and all Doppler indices of AoI with the overall adverse perinatal outcome was seen. The sensitivity of CPR was moderate (63.64%) but higher than most AoI indices. Most AoI Doppler indices (PI, RI, IFI) had higher specificities (100%). AoI PSV and EDV had higher sensitivities than CPR for the prediction of overall adverse perinatal outcome, with AoI PSV having the highest sensitivity (100%). Conclusion CPR shows significant association and moderate sensitivity for prediction of overall adverse perinatal outcome in early FGR; hence recommended in all cases of early FGR. AoI Doppler also appears to have a role in assessment and decision making in FGR in view of high sensitivity and high specificity of AoI indices in the prediction of perinatal outcome. However, larger studies are required to confirm its utility in the management of early FGR.
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