纳米凝胶
生物相容性材料
多糖
壳聚糖
化学
纳米技术
右旋糖酐
药物输送
甲壳素
毒品携带者
纳米载体
自愈水凝胶
化学工程
材料科学
有机化学
生物医学工程
工程类
医学
作者
Zhong Zhang,Guoying Hao,Chen Liu,Junqing Fu,Dan Hu,Jianhui Rong,Xingbin Yang
标识
DOI:10.1016/j.foodres.2021.110564
摘要
Nanogel carriers are rapidly emerged as a major delivery strategy in the fields of food, biology and medicine for small particle size, excellent solubility, high loading, and controlled release. Natural polysaccharides and proteins are selected for the preparation of biocompatible, biodegradable, low toxic, and less immunogenic nanogels. Different polysaccharides and proteins form complex nanogels through different interaction forces (e.g., electrostatic interaction and hydrophobic interaction). The present review pursues three aims: 1) to introduce several well-known dietary polysaccharides (chitosan, dextran and alginate) and proteins (whey protein and lysozyme); 2) to discuss the types, preparation methods, chemical interactions and properties of various biocompatible complex carriers; 3) to present the application and prospect of polysaccharide-protein complex in bioactive ingredient delivery, nutrient encapsulation and flavor protection. We expect that the integration with nano-intelligent technology will improve the functional ingredient loading, recognition specificity and controlled release capabilities of polysaccharide-protein nanocomposites to generate new intelligent nanogels in the field of food industry in the future.
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