An Air/Water‐Stable Tridentate N‐Heterocyclic Carbene‐ Palladium(II) Complex: Catalytic CH Activation of Hydrocarbons via Hydrogen/Deuterium Exchange Process in Deuterium Oxide

While developing novel catalysts for carbon-carbon or carbon-heteroatom coupling (N, O, or F), we were able to introduce tridentate NHC-amidate-alkoxide palladium(II) complexes. In aqueous solution, these NHC-Pd(II) complexes showed high ability for C-H activation of various hydrocarbons (cyclohexane, cyclopentane, dimethyl ether, THF, acetone, and toluene) under mild conditions.