类黄酮
化学
作用机理
螯合作用
水溶液中的金属离子
生物活性
组合化学
金属
生物化学
有机化学
抗氧化剂
体外
作者
Stalin Selvaraj,Sridharan Krishnaswamy,Venkappayya Devashya,Swaminathan Sethuraman,Uma Maheswari Krishnan
摘要
Abstract Flavonoids are among the most investigated phytochemicals due to their pharmacological and therapeutic activities. Their ability to chelate with metal ions has resulted in the emergence of a new category of molecules with a broader spectrum of pharmacological activities. However, the biological significance of these flavonoid–metal ion complexes is yet to be completely explored. Moreover, no concerted efforts have been made to elucidate their molecular targets and mechanisms of action. This review attempts to provide a snapshot of the various biological activities reported for flavonoid–metal ion complexes and their potential as therapeutic agents. Understanding the mechanism of action and the influence of structure will provide a strong basis to design novel flavonoid–metal ion complexes of therapeutic significance.
科研通智能强力驱动
Strongly Powered by AbleSci AI