Cost of chemotherapy‐induced thrombocytopenia among patients with lymphoma or solid tumors

医学 化疗 入射(几何) 回顾性队列研究 血小板输注 成本效益 外科 总成本 并发症 队列 血小板 内科学 物理 风险分析(工程) 光学 经济 微观经济学
作者
Linda S. Elting,Scott B. Cantor,Charles G. Martin,Lois Hamblin,Danna Kurtin,Edgardo Rivera,Saroj Vadhan‐Raj,Robert S. Benjamin
出处
期刊:Cancer [Wiley]
卷期号:97 (6): 1541-1550 被引量:52
标识
DOI:10.1002/cncr.11195
摘要

Abstract BACKGROUND The purpose of this study was to estimate the mean incremental cost of chemotherapy‐induced thrombocytopenia and the drivers of cost. Another goal was to estimate the impact of depth and duration of thrombocytopenia on the cost of thrombocytopenia. METHODS A retrospective cohort, consisting of a random sample of 75 solid tumor or lymphoma patients who developed chemotherapy‐induced thrombocytopenia (≤ 50,000 platelets per μl), was chosen. The number of each type of resource used during 217 cycles with and 300 cycles without thrombocytopenia were multiplied by the cost of each resource and summed to yield the total cost of care (in 1999 dollars from the provider's perspective). RESULTS Compared with cycles without thrombocytopenia, the mean incremental cost of thrombocytopenia was $1037 per cycle. However, 60% of cycles were usual cost, with a mean cost of thrombocytopenia of $43 per cycle less than control cycles. Twelve percent of cycles were high cost (mean incremental cost = $612 per cycle); 28% were very high cost (mean incremental cost = $3519). The excess cost during high‐cost cycles was due to high consumption of prophylactic platelet transfusions and during very high‐cost cycles to both higher platelet transfusion consumption and to a high incidence of major bleeding episodes. CONCLUSIONS Although thrombocytopenia is a common complication of chemotherapy, only 40% of cycles with thrombocytopenia would be considered high or very high cost. Interventions targeted at this subset of cycles could significantly reduce the cost of thrombocytopenia provided they are initiated early enough in the chemotherapy experience to be effective. Cancer 2003;97:1541–50. © 2003 American Cancer Society. DOI 10.1002/cncr.11195
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
PDF的下载单位、IP信息已删除 (2025-6-4)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
寒风完成签到,获得积分10
刚刚
晴云发布了新的文献求助10
1秒前
朴素羊完成签到 ,获得积分10
3秒前
3秒前
小马甲应助小王采纳,获得10
3秒前
俭朴羊青完成签到,获得积分10
4秒前
张张完成签到,获得积分10
6秒前
tomorrow完成签到 ,获得积分10
7秒前
糖炒栗子完成签到,获得积分10
8秒前
现代期待完成签到,获得积分10
8秒前
小黎完成签到,获得积分10
9秒前
呼呼呼完成签到,获得积分10
9秒前
无花果应助晴云采纳,获得10
9秒前
寸草的晖完成签到,获得积分10
10秒前
11秒前
11秒前
11秒前
小燕子发布了新的文献求助10
12秒前
13秒前
顺顺完成签到,获得积分10
14秒前
jiachun完成签到,获得积分10
14秒前
jiaolulu发布了新的文献求助10
14秒前
小王发布了新的文献求助10
15秒前
queen814完成签到,获得积分10
15秒前
简单发布了新的文献求助10
16秒前
一只呆果蝇完成签到,获得积分10
16秒前
Eternity完成签到,获得积分10
17秒前
研友_VZG7GZ应助落后从阳采纳,获得10
17秒前
乐观寻绿完成签到,获得积分10
18秒前
Hover完成签到,获得积分0
18秒前
莫晓岚完成签到,获得积分10
18秒前
123完成签到 ,获得积分10
19秒前
所所应助JSY采纳,获得30
19秒前
默默的立辉完成签到,获得积分10
19秒前
Yh完成签到,获得积分10
19秒前
引子完成签到,获得积分10
21秒前
机智的阿振完成签到,获得积分10
22秒前
KatzeBaliey完成签到,获得积分10
23秒前
量子星尘发布了新的文献求助10
24秒前
yar应助大饼采纳,获得10
25秒前
高分求助中
【提示信息,请勿应助】关于scihub 10000
Les Mantodea de Guyane: Insecta, Polyneoptera [The Mantids of French Guiana] 3000
徐淮辽南地区新元古代叠层石及生物地层 3000
The Mother of All Tableaux: Order, Equivalence, and Geometry in the Large-scale Structure of Optimality Theory 3000
Global Eyelash Assessment scale (GEA) 1000
Picture Books with Same-sex Parented Families: Unintentional Censorship 550
Research on Disturbance Rejection Control Algorithm for Aerial Operation Robots 500
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 生物化学 物理 内科学 纳米技术 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 冶金 细胞生物学 免疫学
热门帖子
关注 科研通微信公众号,转发送积分 4038368
求助须知:如何正确求助?哪些是违规求助? 3576068
关于积分的说明 11374313
捐赠科研通 3305780
什么是DOI,文献DOI怎么找? 1819322
邀请新用户注册赠送积分活动 892672
科研通“疑难数据库(出版商)”最低求助积分说明 815029