神经生长因子
内分泌学
内科学
化学
骨化三醇
信使核糖核酸
生长因子
生物
医学
受体
基因
生物化学
维生素D与神经学
作者
Frédéric Jehan,Isabelle Neveu,N Barbot,Lise Binderup,Philippe Brachet,Didier Wion
标识
DOI:10.1016/0922-4106(91)90072-p
摘要
The effect of MC903, an analogue of 1,25-dihydroxyvitamin D3, on the expression of the nerve growth factor (NGF) gene has been studied in L cells. MC903 induces an increase in both NGF mRNA and protein with a time course similar to that obtained with 1,25-dihydroxyvitamin D3. This finding points to the potential importance of 1,25-dihydroxyvitamin D3 derivatives in the treatment of NGF-sensitive disorders.
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